Posts Tagged ‘paper of the month’

Understanding how the ear can detect sound, particularly faint sounds, has long been perplexing for biologists. The organ of Corti, the anatomical structure within the ear that detects sound, is known to vibrate in response to sound. However, monitoring these vibrations has been difficult, as cells are positioned in within the choclea, deep within the skull. Alfred Nuttall, PhD, director of the Oregon Hearing Research Center, and collaborators from across OHSU worked together to develop … Read More

October 2010′s School of Medicine News features “Defective fatty acid hydroxylase leads to a novel form of neurodegeneration with brain iron accumulation” as its Paper of the Month. This month’s selection, published in Annals of Neurology, is based on research  by Michael Kruer, MD, a fellow in neurodevelopment pediatrics, Susan Hayflick, MD, Professor and Chair, Department of Molecular & Medical Genetics, and colleagues in the Department of Molecular & Medical Genetics. In the paper, the … Read More

September 2010′s School of Medicine News features “Soluble repulsive guidance molecule c/hemojuvelin is a broad spectrum bone morphogenetic protein (BMP) antagonist and inhibits both BMP2- and BMP6-mediated signaling and gene expression” as its Paper of the Month. This month’s selection, published in the Journal of Biological Chemistry, is based on research by Mahta Nili, Doctoral Student, Ujwal Shinde, PhD, Associate Professor, and Peter Rotwein, MD, Professor, from the Department of Biochemistry and Molecular Biology. The … Read More

August 2010’s School of Medicine News features “Dynamic-contrast-enhanced-MRI with extravagating contrast reagent: Rat cerebral glioma blood volume determination” as its paper of the month. This month’s selection, published in the Journal of Magnetic Resonance, was led by Charles Springer, PhD, Director Emeritus, OHSU Advanced Imaging Research Center. The paper demonstrates how OHSU researchers are changing the way scientists use diagnostic drugs to pinpoint diseases such as cancer using magnetic resonance imaging (MRI)–which is advantageous because … Read More

Stephen Hansen, Ph.D., and his team in the Department of Biomedical Engineering explore the fine line between blood clotting and uncontrollable bleeding in the School of Medicine’s July Paper of the Month: “Safety and antithrombotic efficacy of moderate platelet count reduction by thrombopoietin inhibition in primates.” By lowering blood platelet production in nonhuman primates, the researchers discovered that even a slight reduction of platelets within the normal range, reduced clotting–but also prevented the opposite: excessive … Read More

The School of Medicine’s February 2010 Dean’s Update features “Molecular imaging of the initial inflammatory response in atherosclerosis: Implications for early detection of disease” as its Paper of the Month. This month’s selection, published in Arteriosclerosis, Thrombosis and Vascular Biology, was written by an investigative group* from the OHSU Cardiac Imaging Laboratory led by Jonathan Lindner, MD, Professor, OHSU Department of Medicine, Division of Cardiovascular Medicine. According to the School of Medicine’s newsletter, the study … Read More

Starting this month, the School of Medicine will highlight a recently published  paper to call attention to exemplary research at OHSU. This month’s paper is titled Aldosterone mediates activation of the thiazide-sensitive Na-Cl cotransporter through an SGK1 and WNK4 signaling pathway (Journal of Clinical Investigation). The authors are: David J. Rozansky – MD, Associate Professor, Pediatrics Tonya Cornwall – Research Associate, Pediatrics Shaunessy Rogers – Research Assistant, Nephrology & Hypertension Yong-Feng Yang – Senior Research … Read More