Researchers at the Oregon National Primate Research Center have created a new vaccine development technique using a solution previously thought too damaging to be useful in vaccine production. Mark Slifka, Ph.D., and colleagues have successfully utilized hydrogen peroxide as a virus inactivator in the generation of three distinct vaccines. Vaccines for West Nile, Lymphocytic choriomeningitis, and vaccinia viruses have been created using this new technique, which supports the researchers’ claims that this could truly be a new platform technology … Read More
Don’t forget to send in your letters of intent for the following pilot funding opportunities from Oregon Clinical and Translational Research Institute (OCTRI) and the Oregon National Primate Research Center (ONPRC). Deadlines vary – See below or follow the links to the full requests for proposals for more information. Pilot Project Funding for Catalyzing Translational Research Letters of intent due: March 26, 2012 – Up to $100,000 Seeks collaborative, multidisciplinary projects that will lead to … Read More
The Oregon Clinical and Translational Research Institute (OCTRI) and the Oregon National Primate Research Center (ONPRC) have issued the following requests for proposals for pilot funding: ONPRC/OCTRI Collaborative Research Program Description: Provides pilot funding to encourage the use non-human primates (NHP) or NHP-derived materials for new collaborative projects that will lead to new external funding of research with clear translational outcomes. Priority will be given to new collaborations between established investigators at ONPRC and basic … Read More
OHSU researchers, led by Shoukrat Mitalipov, Ph.D., associate scientist at the Oregon National Primate Research Center, have produced the world’s first chimeric monkeys, developed from stem cells taken from two different embryos. This is an important development, not because the researchers plan to develop human chimeras, but because the study reveals new information about different stages of embryo cells. For example, while cells from either early-or later-stage embryos can be combined to create a chimeric … Read More
Back in 2007, Shoukhrat Mitalipov, Ph.D., a researcher at OHSU’s Oregon National Primate Research Center, received international attention for developing a novel method for cloning stem cells. Dr. Mitalipov’s method involved transplanting DNA from an individual’s skin cells into an egg that could develop into various other cell types—no embryonic stem cells needed. More recently, the U.S. Department of Commerce has issued a patent for Dr. Mitalipov’s stem cell cloning method. Why is the patent … Read More
Monday, October 3, 2011, is the second and final seminar at the Oregon National Primate Research Center (ONPRC) presenting benchtop devices for next-generation sequencing. Ion Torrent will be presenting the Personal Genome Machine at 4 p.m. in the Neurological Sciences Institute (NSI) first floor seminar room. Scientists that are currently using (or planning to use) next-generation sequencing are particularly encouraged to attend. Since there is an interest in purchasing one of these systems as shared … Read More
This month’s featured research, published in the Annals of Neurology, identifies a disease in non-human primates that has many similarities to multiple sclerosis (MS). The research is the result of a collaborative effort between multiple departments at OHSU and the Oregon National Primate Research Center (ONPRC). Like MS, Japanese macaque encephalomyelitis (JME) affects a small percentage of non-human primates. Since the macaque colony at ONPRC was established in 1965, only 56 cases of spontaneous, MS-like … Read More
Researchers from the Oregon National Primate Research Center (ONPRC) have found the first naturally occurring disease in nonhuman primates that is comparable to multiple sclerosis in humans. The disease, they found, is caused by a type of herpes virus, which may also trigger multiple sclerosis in humans. The authors of the paper, published Tuesday in the Annals of Neurology, hope that this discovery will give insight into the cause of multiple sclerosis, and ultimately lead … Read More
An estimated one in three adults in the U.S. is obese, but its treatment may be more complex than you might think, according to OHSU’s Kevin Grove, PhD, who has been featured in the New York Times and on ABC’s Nightline for his research on obesity and diabetes in “couch-potato” primates. Since we blogged about Dr. Grove’s research back in February, OHSU’s communications team has created a fact sheet about obesity and OHSU’s research on … Read More
The Primate Center Molecular Core has purchased an Applied Biosystems OpenArray system that performs high throughput genotyping and qPCR. This system is optimal for when you have hundreds and thousands of samples on which you want to perform from 24 to 1000 qPCR or genotyping reactions on each sample. The systems is also ideal for predefined panels of gene quantification. Loading of samples is robotic so minimal sample preparation is involved and thousands of reactions … Read More
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