Posts Tagged ‘OHSU Researchers’

Hope for MS patients through understanding roots of the disease in monkeys

New research led by Scott W. Wong, Ph.D., senior scientist, Vaccine and Gene Therapy Institute; interim division chief, Division of Pathobiology and Immunology at the Oregon National Primate Research Center; and professor, OHSU’s Department of Molecular Microbiology and Immunology, describes the similarities between multiple sclerosis and a unique, spontaneous paralytic disease that occurs in nonhuman primates. This model opens the door to discovering the mechanisms driving MS in humans. The model, called Japanese macaque encephalomyelitis, … Read More

Training Opportunity for Responsible Conduct of Research

Are you participating in an NIH training grant award or fellowship? Do you need RCR training? The Oregon Clinical and Translational Research Institute (OCTRI) is offering an 8-hour seminar that meets RCR requirements for Ks, Ts, and other career development or individual fellowship grants. This seminar is an interactive and practical experience  focused on addressing real issues that have arisen in the course of your research. These may be related to ethics, integrity, or regulatory … Read More

Researchers discover a network of genes that control when puberty begins

Researchers at OHSU and the University of Pittsburgh have identified members of an elaborate superfamily of genes that regulate the timing of puberty in highly evolved nonhuman primates. The Zinc finger, or ZNF, gene family comprises approximately 800 individual genes. A handful of genes in this network serve as a “neurobiological brake” that delay the activation of hypothalamic genes responsible for launching puberty until the end of childhood, thereby preventing the premature awakening of the process. The … Read More

OHSU Doernbecher researchers receive Gates Foundation grant to advance tuberculosis vaccine research

David Lewinsohn, M.D., Ph.D., in the Papé Family Pediatric Research Institute at OHSU Doernbecher Children’s Hospital, has been awarded a $3 million grant from the Bill & Melinda Gates Foundation to study whether a particular group of infection-fighting cells, known as T cells, may be viable for the development of a vaccine aimed at combatting the global tuberculosis epidemic. According to the World Health Organization’s 2015 global report, TB claimed 1.5 million lives in 2014 … Read More

Murine CRISPR/Cas9 pilot program updates

CRISPR/ Cas9 gene editing is rapidly becoming the state of the art for mouse genome engineering. During the last year, the OHSU Transgenic Mouse Models Core has successfully used this technology to generate both targeted gene knock-outs and point mutation knock-ins for its clients. The Transgenic Mouse Models Core has revised its CRISPR pricing structure for 2016. Non-homologous end joining-based gene knock-outs for OHSU investigators will be $2100 per project (150 injections), with the user … Read More

Who’s new at OHSU? Marina Guizzetti, Ph.D.

Marina Guizzetti, Ph.D., is an associate professor in the Department of Behavioral Neuroscience at OHSU and a research biologist with the Portland VA Health Care System. Her research focuses on the neurodevelopmental effects of alcohol on the developing brain, specifically looking at Fetal Alcohol Spectrum Disorders. Where are you from originally? I’m from northern Italy and also where I was educated. I got my degree at the University of Pavia just south of Milan. This … Read More

Announcing Data Science forums for OHSU researchers

Do you have an opinion about the future of data science or research informatics at OHSU? If so, this is your chance to provide input for OHSU’s new data science initiative. OHSU will be investing in clinical and research informatics in the next several years, and the institution wants to hear from you about what is needed to succeed. You’re invited to attend a series of three, 90-minute forums across campus to solicit input from … Read More

Who’s new at OHSU? Khaled Tolba, M.D.

Khaled Tolba, M.D., is an assistant professor of medical oncology, division of hematology-oncology and has been at OHSU since January. His research focuses on developmental therapeutics and early clinical trial development for lung, and head and neck cancer. In addition to helping facilitate access to the latest clinical trials, Tolba also cares for patients with these cancers, providing tailored treatments including immune therapy and molecular targeted therapies. Where are you from originally? I was born, raised, … Read More

Gene Therapy Symposium, Nov. 4

The OHSU Gene Therapy Working Group and the Pape’ Family Pediatric Research Institute invite you to attend the 4th Annual Gene Therapy Symposium, an afternoon event to showcase OHSU’s Gene Therapy research excellence. Gene Therapy at OHSU Wednesday, Nov. 4 2 to 6:30 p.m.  Doernbecher Children’s Hospital, Vey Conference Center  Register here by Oct. 28 This half day symposium will feature “Emerging prospects for gene therapy for muscular dystrophy,” a keynote address from Jeffrey S. Chamberlain, Ph.D., McCaw … Read More

Who’s new at OHSU? Kathleen Humphries, Ph.D.

Kathleen Humphries, Ph.D., recently joined OHSU as director of the University Center for Excellence in Developmental Disabilities and associate director for research and academic affairs at the Institute on Development & Disability (IDD). Her research focus includes nutrition behavioral interventions for persons with disabilities and their support teams as well as health and developmental outcomes related to food habits and nutrition. Where are you from and where did you study? I’m from Ohio originally, but … Read More

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