Posts Tagged ‘OHSU researchers’

OHSU research yields insight into aspirin’s anti-cancer effect

The anti-inflammatory and anti-platelet properties of aspirin have made it the subject of intensive investigation for over a century. More recently, aspirin use has been correlated with reduced long-term risk of some cancers, particularly colorectal cancer. The reasons remain unknown, as does the degree to which the effect comes from direct inhibition of cancer cells and how much is due to inhibition of platelet activation and function. A study recently completed by a team of OHSU researchers and published in the American … Read More

David Huang, M.D., Ph.D., receives National Academy of Inventors award

OHSU Casey Eye Institute researcher David Huang, M.D., Ph.D., has been named a Fellow of the National Academy of Inventors. Academic inventors and innovators elected to the rank of NAI Fellow were nominated by their peers for outstanding contributions to innovation in areas such as patents and licensing, innovative discovery and technology, significant impact on society, and support and enhancement of innovation. Huang, the Peterson Professor of Ophthalmology and Professor of Biomedical Engineering at OHSU, … Read More

Carsten Schultz and lab develop new imaging platform for profiling cell signaling networks

Cellular development, tissue repair, immunity, and normal homeostasis rely on cells perceiving and appropriately responding to their microenvironment. While significant knowledge exists on the individual aspects of these cell signaling pathways, the question persists on how cell signaling networks integrate and process information from multiple extracellular cues. Understanding these processes may help develop therapies to more effectively treat diseases such as cancer and diabetes that result from errors in processing information. A study published December … Read More

OHSU’s Erick Turner and team finalists for Open Science Prize: voting open through Jan. 6

Alongside the growing availability of high-value open data for research are key obstacles — discoverability and the ability to access and use that data. The global science competition Open Science Prize was launched by the Wellcome Trust, US National Institutes of Health, and the Howard Hughes Medical Institute to encourage new ways to remove these obstacles. In the first phase of this new initiative, six international teams received prizes to develop prototypes. The teams presented … Read More

New OHSU research suggests possible target in fight against Alzheimer’s

In most of the human body, the lymphatic system clears away waste and toxins. The brain, however, has no lymphatic vessels. Its waste, including plaques associated with Alzheimer’s disease, is cleaned instead by cerebrospinal fluid recirculating through brain tissue. Over the course of five years, research in the lab of Jeffrey Iliff, Ph.D., has defined this brain-wide paravascular pathway, called the glymphatic system. Iliff’s team has found that this recirculation is modulated by sleep and also that, as the brain ages, this … Read More

Oregon Hearing Research Center scientists featured on front page of the Oregonian

The Oregonian featured OHSU’s Oregon Hearing Research Center on page 1 of its Nov. 25 print version and on its website, highlighting the Center’s four scientists with hearing loss. Peter Steyger, Ph.D., Lina Reiss, Ph.D., John Brigande, Ph.D., and Alfred Nuttall, Ph.D., belong to OHSU’s team of researchers investigating causes and solutions to hearing loss. Their research ranges from toxicity of certain pharmaceutical drugs to genetic therapies to prevent deafness through treatments in utero. Also featured … Read More

New OHSU research provides key insight about mitochondrial replacement therapy

No treatments exist for children born with mitochondrial diseases, but a series of discoveries in the OHSU Center for Embryonic Cell and Gene Therapy is making progress on a technique that prevents transmission of these often-fatal genetic diseases, which are passed on from mothers to their children. The latest findings were published on Nov. 30 in the journal Nature. OHSU scientist Shoukhrat Mitalipov, Ph.D., led a team that successfully prevented transmission of genetic defects in … Read More

New study documents role of glial cells in brain

Glial cells, once considered passive bystanders of neural transmission, are now understood to provide support and protection for neurons in the central and peripheral nervous systems. Astrocytes, the most abundant glial cells in the brain, closely associate with neuronal synapses and perform supporting roles in neuronal activity by providing oxygen and sugars and by removing carbon dioxide. New research findings demonstrate a function scientists have proposed but not proven—that astrocytes not only support but actively … Read More

New research suggests travel to Mars may alter cognition

Cosmic radiation during deep space travel could alter the cognitive function and behavior of astronauts on an extended mission — such as a trip to Mars. Cosmic rays are generated in the shockwaves of exploding stars outside our solar system and are composed primarily of ionized atomic nuclei moving at nearly the speed of light. Exposure to this radiation may be unavoidable for astronauts on any future mission to Mars. Results of a study led by … Read More

Who’s new at OHSU? Vinay Prasad

Vinay Prasad, M.D., M.P.H., is a hematologist-oncologist and assistant professor in the OHSU School of Medicine. He is nationally known for his research on health policy, evidence-based medicine, bias, and medical reversal. Clinically, Dr. Prasad specializes in the care of lymphoma patients. He holds appointments in the Department of Public Health and Preventive Medicine and the Center for Health Care Ethics, where he is a Senior Scholar. We sat down with Dr. Prasad to talk about … Read More

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