Posts Tagged ‘OHSU Researchers’

Who’s new at OHSU? Fikadu G. Tafesse, Ph.D.

Fikadu G. Tafesse, Ph.D. is an assistant professor of molecular microbiology and immunology who is working to understand how pathogens utilize host cellular processes during infection. He arrived at OHSU from Boston in February, 2016. Where are you from originally? I was born and raised in Ethiopia and got my undergraduate degree in agriculture there, learning how to grow crops – basic farming. After graduation, I decided to go to Europe to gain more experience and ended … Read More

Researchers study potential treatment to reduce brain swelling after stroke

Brain swelling resulting from a large, acute stroke event causes further damage and can lead to major disability and death, and there are few effect treatment options. Existing drug regimens do not improve survival or functional outcome. Decompressive craniectomy, a surgical procedure to remove part of the skull, allowing the brain to swell without being squeezed, improves outcomes in some patients but increases survival with major disability in others. Future treatments are likely to target pathways involved in brain swelling, and … Read More

OHSU researchers elucidate the role of diet in treating people with MS

A first-time controlled clinical trial found that a low-fat, plant-based diet significantly improved the health of people with multiple sclerosis (MS) by reducing both fatigue and weight. Those improvements go hand-in-hand with fighting some of the most debilitating effects of MS, according to the study’s lead author, Vijayshree Yadav, M.D., a MS neurologist with the Oregon Brain Institute at OHSU. While the new research did not show differences in the MS lesions on the brain … Read More

OHSU Library to sponsor two scholarships for OpenCon 2016

Interested in scientific communication? Want a more open system to share research and data? Then OpenCon 2016 could be the catalyst for you to pursue these passions and the OHSU Library wants to send you to Washington, D.C., where the conference is being held this year, Nov. 12 to 14. OpenCon is designed to teach scientists and scholars from around the world about open access, open data, and open education, and foster a discussion on key issues surrounding scholarly communications and publications. The conference … Read More

Who’s new at OHSU? Nathalie Pamir, Ph.D.

Nathalie Pamir, Ph.D., is an assistant professor in the School of Medicine, Knight Cardiovascular Institute (KCVI), where she focuses on preventive cardiology. Where are you from originally? I’m from a Russian family but I was born in Turkey and spent my childhood there. I then went through the French school system and returned to Turkey to get my undergraduate degree. From there I moved to Vancouver, B.C., where I earned my master’s degree at the … Read More

Study led by OHSU researchers provides evidence of immune therapy efficacy in treating metastatic prostate cancer

Programmed cell death 1 (PD-1) inhibitors have shown anti-tumor activity in patients with melanoma, renal cell, non-small cell lung cancer, and bladder cancer. However, patients with castration-resistant prostate cancer demonstrated no response to such immunotherapies in past studies. Now, a research team led by Julie Graff, M.D., assistant professor and oncologist with the Knight Cancer Institute, has shown clear evidence of meaningful clinical activity for PD-1 blockade in men with metastatic prostate cancer resistant to … Read More

OHSU researchers visualize architecture of the TARP complex

Glutamate receptors are the most prevalent molecular “switches” mediating communication between nerve cells in the brain. They play keys roles in nearly all human behaviors, from learning to memory and movement, as simply a few examples.  Glutamate receptors are also the targets of a broad range of therapeutic agents, from anti-seizure medications to antidepressants. Glutamate receptors do not function alone, however: they form complexes with other proteins called transmembrane AMPA-receptor regulatory proteins, or TARPs. These accessory proteins modulate … Read More

2016 BIP Drug Discovery awardees announced

The Oregon Clinical & Translational Research Institute and OHSU Technology Transfer & Business Development are pleased to announce the funding of two Biomedical Innovation Program  drug discovery awards. A new track supports drug discovery platforms and early stage therapeutic technology projects, including validation of drug targets and the development of small molecules, antibodies, vaccines, or biologics. The BIP provides funds, project management, and mentorship to facilitate the development of innovative technologies at OHSU, and accelerate their translation from … Read More

Who’s new at OHSU? Sudarshan Anand

Sudarshan Anand, Ph.D., is an assistant professor in the School of Medicine’s Departments of Cell, Developmental & Cancer Biology and Radiation Medicine. He arrived at OHSU in March 2014 and is one of a team of researchers at OHSU examining factors that shape the tumor microenvironment. Where are you from originally and what shaped your early career? I was born and raised in India and came to the U.S. in 2001 for graduate school. I … Read More

OHSU investigators uncover factors driving “low-value care”

Waste accounts for roughly 20 percent of spending in the U.S. health care system. A significant portion of that waste is attributed to low-value care – unnecessary tests and treatments that are not only costly but provide little clinical benefit or may even harm patients. However, little was known about the patterns and drivers of this type of care. In a first-of-its kind study, researchers from OHSU’s Center for Health Systems Effectiveness (CHSE), compared low-value … Read More

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