Posts Tagged ‘OHSU researchers’

Oral antibiotics after C-section may reduce infection risk for obese women

The rate of obesity among U.S. women has been increasing, and obesity is associated with an increased risk of surgical-site infection following cesarean delivery. Research by Amy Valent, D.O., assistant professor of obstetrics and gynecology in the School of Medicine, and colleagues at the University of Cincinnati found that the rate of infection for women who received additional oral antibiotics after delivery was 6.4 percent. Women in the placebo group had a 15.4 percent rate … Read More

Despite progress, health disparities remain among racial and ethnic minority groups post-ACA

In a first-of-its-kind study, researchers from OHSU and OCHIN report that community health centers in states that expanded Medicaid coverage experienced a decrease in uninsured visits and an increase in Medicaid-insured visits compared with non-expansion states. The research, published in the Annals of Family Medicine. also found that Hispanic patients have the highest rates of uninsured clinic visits, both before and after Affordable Care Act expansion. Read the full story on the OHSU News Hub. Heather Angier, … Read More

Motor neurons aren’t the only site for restoring locomotive function

Amyotrophic lateral sclerosis is the most common adult onset motor neuron disease for which there is no cure or treatment that significantly extends life. ALS causes the death of neurons that control voluntary muscles and is characterized by gradually worsening weakness, loss of motor function and, when the individual can no longer breathe, death. The only FDA-approved drug used to treat ALS prolongs on average the lifetime of a patient by two to three months. A feature in neurodegenerative diseases, including about 90 percent … Read More

OCTRI receives $37 million grant from the National Center for Advancing Translational Sciences

The National Institutes of Health has named OHSU’s Oregon Clinical & Translational Research Institute a recipient of 2017 Clinical and Translational Science Award (CTSA) grant. OCTRI was an original recipient of the program in 2006, and the new award provides more than $37 million in federal funding to support the Institute’s work over the next five years. OCTRI helps accelerate the translation of research into clinical use, medical practice and health policy, with the goal of improving the health of the … Read More

New findings show retinal development requires the protein dystroglycan

OHSU scientists have published a paper that provides new information on retinal development and visual system abnormalities present in dystroglycanopathy, a form of muscular dystrophy that results from defective function of the protein dystroglycan. Patients with severe forms of dystroglycanopathy frequently experience visual system problems in addition to other neurodevelopmental abnormalities. There is some understanding of dystroglycan’s influence on brain development, but its role in regulating retinal development has remained poorly understood. A team led … Read More

Study suggests cosmic rays pose long-term risks for astronauts

For astronauts on long missions in deep space, the brain’s response to radiation exposure is an important concern. Cognitive and other impairments put crews at risk during space travel and may pose significant health hazards to space flight crews for years after a mission. A unique feature of the space radiation environment is the presence of galactic cosmic rays and solar particle events, both of which involve protons. Exposure to these will likely impact multiple … Read More

Study in Nature demonstrates method for repairing genes in human embryos that prevents inherited diseases

In a paper published in Nature today, August 2, 2017, Shoukhrat Mitalipov, Ph.D., reported the successful removal of a lethal genetic defect in human embryos. Read the OHSU News story on Mitalipov’s new research. The gene-editing technique described in this study could one day provide an avenue for people with known heritable disease-causing genetic mutations to eliminate the risk of passing the disease to their children. The study also demonstrated a way to overcome a crucial problem in … Read More

Research advocacy update: Owen McCarty represents Oregon at the American Heart Association You’re the Cure event

Owen McCarty, Ph.D.,FAHA, represented Oregon in a Washington D.C. research advocacy event in July. He joined a group of 330 advocates who met with 284 legislative offices as part of the 2017 American Heart Association You’re the Cure on the Hill. The team from Oregon included two patient advocates, Jane Staniford and Kellie Hill (pictured), as well as the Oregon AHA Director of Government Relations & Affairs, Christina Bodamer (left). They had a chance to meet with … Read More

Tracing the mechanisms of pain and empathy for pain

A new study finds a potential neural overlap between physically induced and socially transferred increased sensitivity to pain, or hyperalgesia. Previous research has shown that pain sensitivity associated with alcohol withdrawal can be communicated to nearby individuals by olfactory cues. But how this social transfer of pain occurs is not known. Scientists at OHSU have now demonstrated that pain and empathy for pain activate partially overlapping regions of the brain in mice. Andrey Ryabinin, Ph.D., … Read More

Modifying a battlefield dressing to prevent maternal death

Every day around the globe, more than 830 women die from preventable causes related to pregnancy and childbirth. Ninety-nine percent of these deaths occur in developing countries, where resources are limited and childbirth occurs outside of the health care system. Postpartum hemorrhage is one of the primary causes of maternal death and the leading cause of death for new mothers in developing countries. A major challenge in treating postpartum hemorrhage is that it is not … Read More

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