Posts Tagged ‘OHSU researchers’

Ev McClendon, Ph.D., neuroscientist (and sheep OBGYN), featured in OHSU In the Lab

Premature babies are at risk for disabilities that can last a lifetime. With sheep from a local farmer, Ev McClendon, Ph.D., has made some groundbreaking discoveries about what causes these cognitive and learning problems — and what might be done to prevent them. A neuroanatomist working in the lab of Stephen Back, M.D., Ph.D., McClendon was the lead author on a recent paper that demonstrated low oxygen, more than low blood flow, causes major disturbances in brain development. What are you studying … Read More

Three questions for Alejandro Aballay

Alejandro Aballay, Ph.D., joined OHSU as chair of the Department of Molecular Microbiology and Immunology in September 2017. He came to OHSU from Duke University Medical Center, where he was a professor of molecular genetics and microbiology and director of the Center for Host-Microbial Interactions. What projects are you currently working on and are there opportunities collaboration? Overall, our research project is highly interdisciplinary so there are numerous opportunities for synergistic interactions with fellow faculty. In the broad … Read More

OHSU Researchers: Core Pilot Funds – Update

Update 2 – December 1, 2017:  The University Shared Resources program would like to thank those who applied for FY2018 USR Pilot Fund Grants. They received nearly double the number of applications from 2016 and are working to process them all as quickly as possible. They hope to notify all applicants with a decision on or before Friday, December 8, 2017–and they appreciate the interest in this program. Stay tuned for future opportunities. Update: the deadline for this funding opportunity has … Read More

New treatment may address imatinib-resistant tumors

Each year, 3,000 to 6,000 people are diagnosed with gastrointestinal stromal tumor (GIST)—the most common sarcoma of the gastrointestinal tract. Imatinib myeslate, or Gleevec®, has proved to be a highly effective therapy for many patients with GIST, although long-term survival is poor due to the development of imatinib-resistant GIST mutation types. Research recently published in Science Translational Medicine demonstrated promising results for a new treatment, BLU-285, which specifically targets two of the most common imatinib-resistant GIST mutations: KIT … Read More

New insights into the neural representation of reward and punishment

The ability to weigh the risk of punishment relative to the risk of reward is critical to our ability to make decisions. New research by Bita Moghaddam, Ph.D., provides fresh insight into how the brain processes reward and punishment. Little has been known about the neural representation of punishment risk during reward-seeking behavior. For people to make the best decisions, our brains need to appropriately represent the punishment that lurks during reward-seeking actions. An exaggerated neural representation … Read More

NIMH new innovator award recognizes leader in autism research

The National Institutes of Mental Health has awarded a highly competitive research grant to Brian J. O’Roak, Ph.D., assistant professor of molecular and medical genetics in the OHSU School of Medicine. The grant, $2.5 million over five years, is part of the NIMH Biobehavioral Research Awards for Innovative New Scientists, or BRAINS, program and recognizes O’Roak as an autism research innovator who has the potential to transform the field. The BRAINS program was established in 2009 … Read More

Functional brain connectivity: Fair lab shines new light on the role of genetics

Every person has a distinct pattern of functional brain connectivity — a connectotype, or brain signature. A team led by Damien Fair, Ph.D., P.A.-C., reports a new methodology that reliably identifies and tracks these individual brain signatures. The research shows that, while individually unique, each connectotype demonstrates both familial and heritable relationships. The results were published in Network Neuroscience. The work builds on continuing research in the Fair lab. In a previous study, the team showed … Read More

Study by Back lab brings new understanding of brain development in preterm children

Premature infants are at risk for a range of life-long cognitive and learning disabilities – disabilities that for years have been attributed to impaired blood flow to the brain. A new study published in the Journal of Neuroscience challenges more than a decade of scientific study and this clinical understanding of brain development in preterm children. OHSU Doernbecher Children’s Hospital researchers led by Stephen Back, M.D., Ph.D., found that, while limited blood flow may contribute … Read More

Tissue engineering: Avathamsa Athirasala featured in OHSU In the Lab

More than 15 million root canals are performed each year in the United States. Current root canal procedures remove infected dental tissue and replace it with inert synthetic biomaterials, eliminating the tooth’s blood and nerve supply. Now, OHSU researchers have proven that fabrication of artificial blood vessels can be a highly effective strategy for fully regenerating the function of teeth. Read the In the Lab interview with Avathamsa Athirasala on the internal OHSU Staff News blog. Avathamsa Athirasala, … Read More

People Management for Principal Investigators, November 2nd and 3rd

Every principal investigator wants to build and maintain a lab that attracts and retains outstanding trainees and staff members. Juggling this endeavor with everything else the PI must do — writing papers, teaching, mentoring, gaining and maintaining funding, creating collaborative and productive relationships with other PIs — can be challenging at best. This 1.5-day course, led by Melanie Erskine and Rachel Dresbeck from the Office of the Senior Vice President for Research, will help you learn to manage … Read More

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Welcome to the Research News Blog

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