Posts Tagged ‘OHSU researchers’

New treatment may address imatinib-resistant tumors

Each year, 3,000 to 6,000 people are diagnosed with gastrointestinal stromal tumor (GIST)—the most common sarcoma of the gastrointestinal tract. Imatinib myeslate, or Gleevec®, has proved to be a highly effective therapy for many patients with GIST, although long-term survival is poor due to the development of imatinib-resistant GIST mutation types. Research recently published in Science Translational Medicine demonstrated promising results for a new treatment, BLU-285, which specifically targets two of the most common imatinib-resistant GIST mutations: KIT … Read More

New insights into the neural representation of reward and punishment

The ability to weigh the risk of punishment relative to the risk of reward is critical to our ability to make decisions. New research by Bita Moghaddam, Ph.D., provides fresh insight into how the brain processes reward and punishment. Little has been known about the neural representation of punishment risk during reward-seeking behavior. For people to make the best decisions, our brains need to appropriately represent the punishment that lurks during reward-seeking actions. An exaggerated neural representation … Read More

NIMH new innovator award recognizes leader in autism research

The National Institutes of Mental Health has awarded a highly competitive research grant to Brian J. O’Roak, Ph.D., assistant professor of molecular and medical genetics in the OHSU School of Medicine. The grant, $2.5 million over five years, is part of the NIMH Biobehavioral Research Awards for Innovative New Scientists, or BRAINS, program and recognizes O’Roak as an autism research innovator who has the potential to transform the field. The BRAINS program was established in 2009 … Read More

OHSU Researchers: Core Pilot Funds – Deadline extended!

Update: the deadline for this funding opportunity has been extended to November 14. The OHSU University Shared Resources program and the Senior Vice President for Research Office are soliciting grant applications for the USR Core Pilot Fund Grants program. Individual award amounts will vary depending on projected expenses in the proposed core and will be based on need. An upper limit of $10,000 is set for pilot awards utilizing higher-cost core resources and services, although applications of … Read More

Functional brain connectivity: Fair lab shines new light on the role of genetics

Every person has a distinct pattern of functional brain connectivity — a connectotype, or brain signature. A team led by Damien Fair, Ph.D., P.A.-C., reports a new methodology that reliably identifies and tracks these individual brain signatures. The research shows that, while individually unique, each connectotype demonstrates both familial and heritable relationships. The results were published in Network Neuroscience. The work builds on continuing research in the Fair lab. In a previous study, the team showed … Read More

Study by Back lab brings new understanding of brain development in preterm children

Premature infants are at risk for a range of life-long cognitive and learning disabilities – disabilities that for years have been attributed to impaired blood flow to the brain. A new study published in the Journal of Neuroscience challenges more than a decade of scientific study and this clinical understanding of brain development in preterm children. OHSU Doernbecher Children’s Hospital researchers led by Stephen Back, M.D., Ph.D., found that, while limited blood flow may contribute … Read More

Tissue engineering: Avathamsa Athirasala featured in OHSU In the Lab

More than 15 million root canals are performed each year in the United States. Current root canal procedures remove infected dental tissue and replace it with inert synthetic biomaterials, eliminating the tooth’s blood and nerve supply. Now, OHSU researchers have proven that fabrication of artificial blood vessels can be a highly effective strategy for fully regenerating the function of teeth. Read the In the Lab interview with Avathamsa Athirasala on the internal OHSU Staff News blog. Avathamsa Athirasala, … Read More

People Management for Principal Investigators, November 2nd and 3rd

Every principal investigator wants to build and maintain a lab that attracts and retains outstanding trainees and staff members. Juggling this endeavor with everything else the PI must do — writing papers, teaching, mentoring, gaining and maintaining funding, creating collaborative and productive relationships with other PIs — can be challenging at best. This 1.5-day course, led by Melanie Erskine and Rachel Dresbeck from the Office of the Senior Vice President for Research, will help you learn to manage … Read More

Prenatal care for undocumented immigrant mothers leads to improved healthcare for their children

A study led by Jonas Swartz, M.D., in the OHSU School of Medicine found that expanding preventive care in pregnancy for unauthorized immigrant women reduced infant deaths, increased participation in screenings, vaccines. Swartz and senior author Maria Rodriguez, M.D., M.P.H., published the findings in Obstetrics & Gynecology. Unauthorized immigrant women with access to care received 7.2 more prenatal visits, or nearly the nine to 12 visits recommended for a typical pregnancy. They also were 74 … Read More

NRSA Workshop: Technical components – October 24

If you’re planning to apply for a pre- or post-doctoral NRSA fellowship from the NIH in the near future, we encourage you to attend this workshop to learn about essential, non-research elements of your fellowship application. Topics covered include how to set up your proposal in InfoEd, how to develop a budget, how to manage reference letters, biosketches and PMCID numbers, and elements of a great training plan. This upcoming workshop is led by Johanna Colgrove, manager of the MD/PhD … Read More

Welcome to the Research News Blog

Welcome to the Research News Blog

OHSU Research News is your portal to information about all things research at OHSU. Find updates on events, discoveries, and important funding information.

Participation Guidelines

Remember: information you share here is public; it isn't medical advice. Need advice or treatment? Contact your healthcare provider directly. Read our Terms of Use and this disclaimer for details.

Categories

Archives