Posts Tagged ‘NIH News’

New federal policies issued on clinical trials

The NIH is the largest funder of clinical trials in the U.S., investing over $3 billion each year. Standards for scientific rigor and ethical oversight must be exceptionally high because the health and safety of human subjects are at stake. But challenges in the design, efficiency, and reporting of clinical trials are well documented–and may even threaten the progress of biomedicine. In a recent JAMA article,  Kathy Hudson, Ph.D., deputy director for Science, Outreach and Policy … Read More

Learn more about NIH peer review in upcoming online briefings

Have you ever wondered what goes on inside an NIH Study Section and what’s most important to reviewers? The NIH Center for Scientific Review is hosting a series of online briefings in November and December to help you navigate the peer review process and increase your chances of getting funded. The first two briefings will provide fellowship and R01 grant applicants  information on how applications are reviewed for scientific and technical merit. The third briefing will offer information to … Read More

The NIH takes on the challenge of reproducibility: new requirements for 2016

Coming this fall, you will see changes to application instructions for NIH grant applications. Advances in science are built upon previous observations and findings: that’s why replication and corroboration of research results are essential to the scientific process. In response to continued failures in the reliability and reproducibility of published research, the NIH has been analyzing possible causes and exploring potential interventions for some time. A series of pilot projects were run over the past … Read More

NIH seeks additional input on how to sustain the biomedical research enterprise, neuroscience research funding

In recent months, NIH has issued requests for information on various initiatives, resources, and ongoing projects. On April 2,  Jon Lorsch, director of the National Institute of General Medical Sciences, and NIH Deputy Director for Extramural Research Sally Rockey solicited a request titled “Input on Strategies for Optimizing the Impact and Sustainability of Biomedical Research.” Lorsch and Rockey are heading two NIH-wide working groups focused on maximizing the impact and sustainability of NIH-funded research. Rockey’s … Read More

NCI director Harold Varmus to step down

In case you haven’t heard, Harold Varmus, M.D., announced yesterday that he will be stepping down from his position as director of NIH’s National Cancer Institute, effective Mar. 31, 2015. Varmus has led the NCI for nearly five years, and is leaving to pursue scientific work in New York City. In a letter to NCI staff, he outlines some of  NCI’s accomplishments during his tenure, advancements in cancer research, and his future plans.

Notice: NIH revises definition of “clinical trial”

The revision is designed to make the distinction between clinical trials and clinical research studies clearer and to enhance the precision of the information NIH collects, tracks, and reports on clinical trials.  It is not intended to expand the scope of the category of clinical trials. No changes have been made to the NIH definition of a “Phase III clinical trial.” The revised NIH definition of “clinical trial” is: A research study1  in which one … Read More

NIH clarifies the 4-year limit for K99 postdoctoral applicants

The NIH has released a Notice of Clarification in regards to PA-12-042 “NIH Pathway to Independence Award (Parent K99/R00).” The purpose the Notice is to clarify the eligibility requirement that K99 applicants must have no more than 4 years of postdoctoral research experience at the time of the initial application or resubmission or revision.  Specifically, this Notice describes situations in which time is not counted against the 4-year limit. The modified eligibility section now reads: … Read More

New funding initiatives at NIH

With budgets tight as ever, the NIH plans to experiment with new models of funding that boost investigator productivity by proving flexible, longer-term support. (Not unlike the HHMI Investigator Program.) While each institute will be given leeway to design their own programs, in general, applicants will be evaluated on how past accomplishments might shape future research rather than on specific aims. The National Cancer Institute has already issued a call for proposals for its Outstanding … Read More

NIH plans to balance sex in preclinical research

Updated May 20:  Sally Rockey has posted a follow-up note to the Nature article. *** While inclusion of women in NIH-funded clinical studies has led to important discoveries like the need for different doses of medication for men and women, preclinical research lags behind. An article recently published in Nature by Janine Clayton, M.D., director of the Office of Research on Women’s Health at the NIH, and Francis Collins, M.D., Ph.D, director of the NIH, describes the … Read More

NIH announces six new funding opportunities for the BRAIN Initiative

The NIH has launched its new Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative, which is designed to provide support for research projects focused on developing tools and technologies for advancing the understanding of brain circuitry. The first wave of funding opportunities have just been released. Two of the funding opportunities call for developing methods for classifying and accessing the diverse cells and circuits of the brain. Three focus on developing and optimizing technologies for … Read More

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