Posts Tagged ‘Discoveries’

OHSU study advances understanding of TDP-43 protein in ALS

A new study by researchers at the OHSU School of Dentistry advances our understanding of how a protein, TDP-43, impacts gene expression in neurodegenerative diseases like ALS. The researchers altered levels of TDP-43 in fruit flies to directly compare too much versus too little of the protein. Using massively parallel sequencing, they found that loss of TDP-43 results in widespread gene activation and altered splicing. Over expression resulted in decreased gene expression–a finding contrary to … Read More

Knight study on multiple myeloma supports new standard of treatment

A new study, published in the New England Journal of Medicine, found that 63 percent of multiple myeloma patients have a reduced risk of disease progression or death if treated with lenalidomide (Revlimid®) following a stem cell transplant. The study was co-authored by Richard Mariarz, MD, medical director of the Adult Stem Cell Transplantation Program & Center for Hematologic Malignancies at the Knight Cancer Institute. Read the OHSU News Release to learn more.

OHSU researchers recognized for highly cited publications

Two OHSU researchers, Fay Horak, Ph.D., professor of neurology, and Robert Peterka, Ph.D., associate professor of biomedical engineering, were recently recognized by the American Physiological Society for having highly cited publications in the Journal of Neurophysiology. Dr. Horak’s paper, “Central programming of postural movements: Adaptation to altered support-surface configurations,” was one of the top ten cited papers from 1980-1989, and Dr. Peterka’s, “Sensorimotor integration in human postural control,” was one of the top ten from 2000 to 2011. … Read More

OHSU Eye Study: Two medications, similar results, drastically different costs

A recent clinical trial involving researchers from OHSU’s Casey Eye Institute comparing two drugs used to treat age-related macular degeneration (AMD) has shown that both Lucentis and Acastin are nearly equally as effective despite the fact that Avastin costs a fraction of what Lucentis costs. These findings were published this week in the medical journal Ophthalmology. A single dose of Lucentis costs approximately $2,000 whereas one dose of Avastin is around $50. Both drugs are … Read More

OHSU researchers: Do pacifiers really decrease breastfeeding rates?

In 2011, OHSU’s Mother-Baby Unit stopped routine distribution of pacifiers to breastfeeding newborns in accordance with recommendations by the Joint Commission and the American Academy of Pediatrics. Their goal was to increase the number of infants in the unit who were breastfed only and received no supplemental formula. What happened, though, was quite the opposite. When the no-pacifier policy was implemented, the percent of exclusively breastfed infants dropped from 79 to 68 percent. During the … Read More

OHSU researchers discover role of glial cells in regulating neuron development

OHSU researchers Jessica Martin, Ph.D., Alexandra Brown, and Agnieszka Balkowiec, M.D., Ph.D., principal investigator and associate professor of integrative biosciences in the School of Dentistry, have discovered the importance of glial cells in regulating the growth of brainstem neurons. Until now, glial cells had been thought to play a peripheral role in regulating the neurons that control blood pressure and breathing. This new research, published in Neuroscience, shows that glial cells actually play a significant … Read More

Oregon researchers: Tai chi improves balance in Parkinson’s patients

Tai Chi has been shown to improve balance and decrease risk for falls in Parkinson’s patients, according to research published today in the New England Journal of Medicine by a team of Oregon scientists. Elizabeth Eckstrom, M.D., M.P.H., associate professor and director of geriatrics at OHSU, was part of the collaboration, which was led by a scientist from the Oregon Research Institute. The study was one of the first large-scale clinical trials to test the … Read More

Welcome to the Research News Blog

Welcome to the Research News Blog

OHSU Research News is your portal to information about all things research at Oregon Health & Science University. Visit often for updates on events, discoveries, and important funding information.

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