Posts Tagged ‘cores’

OHSU researchers identify structure linked to insulin secretion

It was more than 30 years ago that an ATP-sensitive potassium (KATP ) channel was identified as the key molecular link between glucose metabolism and insulin secretion. The KATP channels sense metabolic changes and translate these energy fluxes into channel gating, which adjusts membrane excitability and regulates insulin secretion. They are the targets of the sulfonylureas, antidiabetic drugs that increase insulin release from beta cells in the pancreas. Genetic mutations of the channel cause several devastating rare … Read More

Participate in FASEB survey on shared research resources

You’re invited to participate in a national survey on research cores. Much of the life-changing research conducted at OHSU is made possible by the university’s more than 20 research cores. Crucial research activities are supported by state-of-the-art equipment, advanced techniques, and specialized expertise in cores ranging from the Cytogenetics Core Laboratory and Biostatistics & Design Program to Proteomics and Massively Parallel Sequencing. The shared research resources model facilitates research activities at institutions around the world. Providers and users … Read More

OHSU researchers develop new model to study S. mutans behavior at protein level

Breakthrough innovation doesn’t happen overnight, and it doesn’t happen without money. OHSU Core Pilot Grants provide OHSU researchers with funds to develop new concepts or methods and to strengthen extramural grant proposals. The program is made possible by University Shared Resources, the School of Medicine, and the Office of the Senior Vice President for Research. In 2016, the University Shared Resources pilot funds provided more than $200,000 for early research by 22 OHSU researchers. With … Read More

Reminder: Applications for University Shared Resources pilot funding due Friday, Oct. 7

This is the final week to submit your applications for the OHSU University Shared Resources Core Pilot Awards program. These awards support OHSU faculty and USR cores by providing pilot funding for principal investigators, especially to support generation of data for new grant applications, as well as to support core development. Applications must be filled out online through OHSU’s Competitive Application Portal (CAP). Full RFA is provided on CAP and can also be found here. Please note: Applicants must … Read More

University Shared Resources pilot award applications due Oct. 7

The OHSU University Shared Resources (USR) program and the Office of the Senior Vice President for Research are soliciting grant applications for the second round of the USR Core Pilot Awards program. These awards support OHSU faculty and USR cores by providing pilot funding for principal investigators, especially to support generation of data for new grant applications, as well as to support core development. The program will provide two types of funding this round: Faculty pilot … Read More

Learn about new technologies and sequencing services in the Integrated Genomics Lab Cores

Join Bob Searles, Massively Parallel Sequencing Shared Resource, and Chris Harrington, Gene Profiling/RNA and DNA Services Shared Resources, who will discuss new genomics technologies available in the cores. Among the new services to be discussed: RNA-seq from FFPE tissue, miRNA sequencing, high throughput DNA and RNA extraction, cell-line authentication, and single cell RNA-seq. All members of the OHSU community are invited to attend.  The Integrated Genomics Lab cores are members of the OHSU University Shared Resources Program. Thursday, … Read More

NIH-funded core facilities – future directions and OHSU’s model

As you know, Sally Rockey has stepped down from her position at NIH where she steered the Office of Extramural Research for five years. During Rockey’s tenure, she launched a blog, “Rock  Talk,” that lent transparency to NIH decision making and allowed the research community to voice their opinions. In her last few Rock Talk postings, Rockey shared some insights and updates on current NIH priorities and resources including a discussion on NIH-supported core facilities. … Read More

Hands-on training available for iLab users, Fridays at 11 a.m.

iLab Solutions software was rolled out over the past six months, bringing to OHSU a web-based tool to help manage scheduling and billing for core research resources. iLab Solutions replaced the Core Ordering and Reporting Enterprise System (CORES). While the rollout overall has been successful, iLab users have requested additional training to learn how to efficiently use the software. A series of GoTo Meeting training sessions have been scheduled for the coming weeks on Fridays … Read More

CRISPR/Cas9 gene editing comes to OHSU

OHSU scientists: you have a new technology available to you–with special pilot pricing available. Several new methods for genome engineering have been introduced in recent years, the most successful of which is the clustered regulatory interspaced short palindromic repeats (CRISPR)/Cas9 system. The OHSU Transgenic Mouse Models Core (TMM) has initiated several preliminary CRISPR pilot projects based in part on a recent campus-wide interest survey. Recently, OHSU’s first F1 mice genetically modified using CRISPR mice were … Read More

iLab Solutions rollout begins July 29 for core resource scheduling and billing

In June, we told you about an upcoming change in the way you interface with core resources at OHSU. Over the next few weeks, OHSU will begin rolling out iLab Solutions, a web-based tool to help manage scheduling and billing for core research resources. iLab Solutions will replace the current Core Ordering and Reporting Enterprise System (CORES). The rollout will happen in phases, with Flow Cytometry, Advanced Light Microscopy, and Massively Parallel Sequencing transitioning to the new system first. … Read More

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