Military Health Systems Research Symposium 2015: Funds available for meeting support

The Military Health Systems Research Symposium–also known as MHSRS–is the most important Department of Defense scientific meeting of the year.  Bringing together all the branches of the armed forces, this joint symposium provides a collaborative environment of exchange among military medical care providers with deployment experience, DoD scientists,  industry, and academic scientists like you, OHSU researchers!  This is a highly interdisciplinary meeting. Areas of interest include combat casualty care, military operational medicine, clinical and rehabilitative medicine, and military infectious disease. The 2015 MHSRS includes new topic sessions on genitourinary injuries and humanitarian emergency response–as well as a special track dedicated to infectious disease.

If you’re interested in attending, the office of the Senior Vice President for Research can help. As with the extremely popular 2014 meeting, this year, the office of the Senior Vice President for Research will pay for meeting-related travel expenses for OHSU researchers whose abstracts are accepted for presentation (you have to actually be presenting to take advantage of this offer). We can also help review abstracts for military relevance and other important details prior to submission.

Abstracts are being accepted through April 3, and you will be notified by May 8th whether your abstract was accepted. Don’t delay! The meeting is usually held the third week of August in Ft. Lauderdale, Florida. And if your abstract is accepted and you want to take advantage of the travel support, we will ask you to fill out a very easy and short application (coming soon). Questions? Write



Department of Defense CDMRP Fiscal Year 2015 funding announced

The Department of Defense office of Congressionally Directed Medical Research Programs (CDMRP) has announced the amount of funds provided for each CDMRP in FY15. Each program will release FYI5 program announcements with detailed descriptions of the individual funding opportunities, evaluation criteria, and submission requirements. All released funding opportunities are available on the CDMRP website, and a full listng of CDMRP funding opportunities can be obtained on the website by performing a basic search using CFDA number 12.420. Future notifications and updates will be published in OHSU’s weekly Funding Alerts. Stay tuned.

Commercialization of an MRI breast cancer detection technology

In 2000, OHSU Advanced Imaging Research Center (AIRC) scientists developed the Shutter-Speed Model (“SSM”) for analysis of Dynamic-Contrast-Enhanced (“DCE-MRI”) data. Later, they realized SSM is not just another pharmacokinetic “model,” but actually a new paradigm (“SSP”). The SSP enables more accurate MRI measure of, among other parameters, Ktrans, the rate constant for contrast agent molecule movement between capillaries and extravascular tissue.

The researchers determined that systematic errors in the standard tracer pharmacokinetic paradigm “SP” Ktrans value, as compared to the SSM Ktrans value, resulted in a large difference, ΔKtrans, in malignant breast tissue, but not in healthy tissue. In other words, the SP underestimates Ktrans precisely in malignant tumors. As reported in the scientists’ 2011 Radiology article, pathologic analyses revealed 20 malignant and 72 benign lesions in 89 high-risk women (age range, 28–83 years), wherein the 92 suspicious lesions received positive findings at current standard of care MRI. Remarkably, the MRI Breast Cancer Detection Technology achieved 98.6% specificity at 100% sensitivity. This could avoid many unnecessary breast biopsies.  Similar prostate cancer results are forthcoming.

Potentially even more important, the lab’s 2014 NMR in Biomedicine paper shows that SSP is capable of mapping intra-tumor metabolic activity, and its focal response to breast cancer therapy. No other technique can do this.

Co-inventor Charles Springer and licensing associate Arvin Paranjpe will co-present this licensing case study at TTBD’s next Lunch & Learn event on Thursday, Feb. 26, from 12 to 1 p.m. in Mackenzie Hall on the Marquam Hill Campus. For a sneak peek into the AIRC group, glance over their hilarious ice bucket challenge video.

Research Administration Information Network monthly meeting, Jan. 15

After a brief winter break, the Research Administration Information Network (RAIN) monthly meeting returns Thursday, Jan. 15, starting at 9:30 a.m. to connect you with the latest announcements, updates, and news from research administration at OHSU.

Meetings are held the third Thursday of each month from 9:30 a.m. to 11 a.m. All are welcome to attend either in person at OHSU Hospital, 8th floor auditorium (8B60), via West Campus videoconferencing, or through the live stream broadcast. This month’s agenda and slides will be posted on the RATE Community site during OHSU’s website refresh project, and then these will return to the RAIN archives along with links to previous recordings of the meeting.

For those not familiar with RAIN, this is a forum for research departments, administrative staff, researchers and anyone else involved in aspects of research administration. At RAIN meetings, we deliver the latest information on NIH updates, award administration, learning opportunities, RDA staffing, and any other notable activity in research administration.

To join the RAIN distribution list, send your request to

Funding Focus – New NIH Biosketch Format, Feb. 19

Research Funding and Development Services will resume hosting monthly Funding Focus workshops every third Thursday beginning in February.  First up: Advice on the new NIH Biosketch format requirements.  In the meantime, for questions on the new format, please see the most recent NIH announcement, which includes instructions and samples. In addition, the Science Experts Network (SciENcv) is now up and running and available to support the new biosketch format. A YouTube video provides instructions for using this tool. Join us for Funding Focus on February 19th from 12 p.m. – 1:00pm in Mackenzie Hall 2201.

CRISPR/Cas9 gene editing comes to OHSU

OHSU scientists: you have a new technology available to you–with special pilot pricing available. Several new methods for genome engineering have been introduced in recent years, the most successful of which is the clustered regulatory interspaced short palindromic repeats (CRISPR)/Cas9 system. The OHSU Transgenic Mouse Models Core (TMM) has initiated several preliminary CRISPR pilot projects based in part on a recent campus-wide interest survey. Recently, OHSU’s first F1 mice genetically modified using CRISPR mice were produced by the TMM (Lev Fedorov, Ph.D., Director), in collaboration with the lab of Peter Barr-Gillespie, Ph.D. At least four different knockout alleles of the Espnl gene were generated; these required less than six weeks from initiation of the project to F0 mice. All alleles transmitted to the F1 generation. In addition, the TMM has currently initiated pilot CRISPR knock-in projects to optimize methodologies for this approach and is prepared to extend pilot program pricing to other OHSU investigators for a limited time. For additional details, visit the TMM website.

OCTRI Research Forum: Survey Design and Tools, Jan. 26

Join the Oregon Clinical and Translational Research Institute, OCTRI, in a monthly research forum that addresses all things clinical and translational research.

Don’t miss January’s topic: Survey Design and Tools
Learn best practices in creating and using a survey for research and discover available tools offered through OCTRI and other resources. Presenters: Cindy Morris, Rob Schuff and Julie Mitchell.

Monday, Jan. 26, 2015
12 to 1 p.m.
Mackenzie Hall 2201

Click here for more information about the OCTRI Research Forum.

OCTRI invites all faculty and staff to discuss issues and solutions to common obstacles in conducting clinical and translational research. Do you have a clinical or translational research question? Let us know, and we’ll do our best to help during these events! Please submit questions and topic requests to Colleen Berreta.

Save the date!
February OCTRI Research Forum: Creating a Budget for Individual Research
Feb. 24, 2015
12 to 1 p.m.
Mackenzie Hall 2201

InfoEd and OGA classes offered Jan. 14


Research Administration Training & Education (RATE) offers a number of courses for the OHSU research community. On the calendar for next week: OGA and InfoEd.

InfoEd’s Proposal Development module is required for preparing and submissions that go through the Office of Proposal and Award Management (OPAM). The electronic Proposed Project Questionnaire (ePPQ) is completed within InfoEd for both and submissions.

Walk step-by-step through the process of creating and routing an NIH R01 proposal in this hands-on computer lab course. Learn to prepare and route non-R01 proposals as well. After building the proposal, you will learn to complete and appropriately route an electronic ePPQ. Wednesday, Jan. 14, 8:30 a.m. to 12 p.m. in BICC 122.

Oracle Grants Accounting
Oracle Grants Accounting (OGA) is OHSU’s system for managing grants and awards accounts, accessible via the Administration Information System (AIS). OGA is overseen by OPAM, which offers a wealth of online resources.

Learners are introduced to the OGA module functionality, and topics include identification and review of OGA financial reports, analysis of financial information, and application of financial data as it pertains to sponsor terms and conditions. Wednesday, Jan. 14, 1 to 4 p.m. in BICC 122.

These classes and other training is searchable in Compass. Contact Margaret Gardner with any questions.


More from the Mello Lab: Buzzed birds slur their songs

Hot on the heels of their ground-breaking bird genome research, the Claudio Mello Lab and colleagues have published new work showing the effects of alcohol on bird vocalization. This PLOS ONE study, by Christopher Olson, Devin Owen, Andrey Ryabinin, and Claudio Mello, showed that alcohol causes the zebra finches to produce song that is quieter and less organized–in effect, it slurs and softens their songs. Interestingly, the alcohol did not affect other areas of their motor coordination.

This discovery made headlines around the globe this past week. Check out the coverage here:

NPR All Things Considered
Slate Magazine

The Washington Post

Los Angeles Times

New York Magazine

Huffington Post

Red Orbit


The Daily Beast

The Independent’s News Matrix

Pioneer News


Utah People’s Post

International Business Times

Frontline Desk

The Register

Tech Times

Press Herald


Boing Boing

Public Radio East

Metro UK

The Daily Meal
Maine News

Capital Berg
Waterloo Region Record
KGMI 790
Business 2 Community
New York Daily News
Full-Time Whistle
Science World Report
South China Morning Post

And many more!

RCR Training Opportunity for NIH Training Grants

The Oregon Clinical and Translational Research Institute (OCTRI) is offering an 8-hour seminar that meets the RCR (Responsible Conduct of Research) requirements of the NIH K award or T award, or any federal or non-federal career development grant. This seminar is an interactive and practical experience that is focused on addressing real issues that have arisen in the course of your research. This may be related to ethics, integrity and regulatory matters; including anything from how you recruit and consent patients to how you keep laboratory methods and determine authorship.

Eligibility: This seminar is also open to training grant faculty who have an RCR requirement; these faculty members can serve as small group facilitators. Priority is given to scholars and trainees funded by an NIH K-award or clinical or translational, postdoctoral T-award or any federal or non-federal career development grant.

Session 1: February 6, 2 to 4 p.m.
Session 2: February 20, 2 to 4 p.m.
Session 3: March 6, 2 to 4 p.m.
Session 4: March 20, 2 to 4 p.m.

Please contact Karen McCracken for questions and to register.

Welcome to the Research News Blog

Welcome to the Research News Blog

OHSU Research News is your portal to information about all things research at Oregon Health & Science University. Visit often for updates on events, discoveries, and important funding information.

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