Volunteers needed for Research Week 2017!

Research Week 2017 is less than a month away, and we need your help! Each year, volunteers play a critical role in in making Research Week a success. Anyone at OHSU can volunteer. It’s a great opportunity to meet people from other areas and gain an understanding of the scope and quality of the research conducted every day at OHSU. There are a number of ways volunteers can help:FPP 21469239 Research Week 2017 ART RGB

  • Check-in desk
    As a Check-in Desk volunteer, you are tasked with greeting attendees and checking in presenters.
  • Poster wrangler
    It’s the Poster Wrangler’s job to see that posters are put up in the right locations.
  • 3MT ballot collector
    Help collect the audience ballots for the “People’s Choice Award” at the end of the Three Minute Thesis competition on Wednesday, May 3.
  • Moderator/backup moderator
    Every oral presentation session will be assigned two volunteers: One Moderator and one Backup Moderator. Moderators are needed to ensure that the pace of the oral presentation sessions are maintained, keeping presenters to their 10-minute time limit.

Go to the Research Week 2017 volunteer website to see what shifts are available and to sign up to be a volunteer. Remember, you can choose as many shifts as you’d like!

Oregon Science Startup Forum, April 22

Registration is now open for the Oregon Science Startup Forum, a one-day course in science entrepreneurship, hosted by the Portland Section of the American Chemical Society.

  • Hear the startup experiences of science entrepreneurs from around Oregon
  • Learn from investors, intellectual property lawyers and experts in turning science into businesses
  • Equip yourself with specific steps to start a successful science businessacs

Saturday, April 22
9 a.m. to 5 p.m. 

Networking Reception 5 p.m. to 7 p.m. 
Collaborative Life Sciences Building

Check out this year’s speaker lineup which includes David Farrell, Ph.D., F.A.H.A., research professor, OHSU Department of Surgery, and founder and chief scientific officer of Gamma Therapeutics, Inc., an Oregon-based early stage biotechnology company developing a novel class of biopharmaceutical and diagnostic test solutions for the cardiovascular disease industry.

Student/postdoc/unemployed registration: $30
General registration: $55

Cost includes meals and refreshments. Questions? Contact jimtung@gmail.com.

Volunteer as a presentation judge at Research Week!

FPP 21469239 Research Week 2017 ART RGBResearch Week 2017 is fast approaching and we need your help! We are looking for 65 faculty, postdocs, and research staff to serve as judges for students who are presenting talks and posters during Research Week, May 1-3. For each session for which you sign up to judge, you’ll be asked to evaluate a maximum of four student presentations (either oral or poster). Visit the sign-up page for a full listing of session dates, times, and research topics that need coverage. To sign up, check the box for the session you’re interested in and click “submit”–once you get into the tool, you’ll be able to see full details. You can also view the session schedule to see which research presentations fit your expertise.

This is a great opportunity to provide valuable feedback to students, and to learn more about the wide-ranging, innovative research taking place here at OHSU.

We kindly ask that you register as soon as possible so we can fill any gaps before the main event. Thank you for contributing to a successful Research Week 2017!

Research Week 2017 conference program now live!

FPP 21469239 Research Week 2017 ART RGBThe detailed schedule for OHSU Research Week 2017 is now live! Be sure to check it out for important dates, times, and abstracts for oral and poster presentations, keynote lectures, and workshops.

Here are a few events you may want to attend:

Promoting your research
Monday, May 1, at 11 a.m., OHSU Auditorium

Attend this interactive workshop on  to learn about best practices for promoting your science and the OHSU resources available to assist you. Find out how to work with OHSU’s media relations and social media departments—and what you can do to promote your research yourself.   

Leading by example: A panel on diversity in science
Wednesday, May 3, at 11:30 a.m., OHSU Auditorium

On join a discussion on women and underrepresented minorities in science. Panelists will share their experiences and describe their career trajectories as well as answer questions from the audience.

Get ready for Research Week with these pre-event workshops
All OHSU researchers (especially students and trainees, but really everyone!) are invited to attend these skill-building seminars to help perfect your presentation for Research Week. Next up: “How to make and present a poster.” Monday, April 10, 3 to 4 p.m., Biomedical Research Building, room 381.

NIH grant workshop: Fine-tuning your research strategy, May 22

2756494307_a0380a96e0_bThis workshop, hosted by Research Funding & Development Services, is for faculty who are writing R01s or R21s. The course will focus on strengthening the research strategy component of the NIH grant application: specific aims, significance and scientific premise, innovation, and approach. We will also cover some of the new forms, such as the Authentication of Biological Variables. The workshop will be led by Rachel Dresbeck, director of research development at OHSU.

NIH grant workshop: Fine-tuning your research strategy

Monday, May 22
8 a.m. to 12 p.m.
Mackenzie Hall, room 2201

There is no cost to attend this workshop, but we do need you to register. Register on Compass.

Questions? Contact funding@ohsu.edu.

New OHSU Notice of Privacy Practices: Implications for Researchers

Do you work with human subjects? You may need to do some spring cleaning. The OHSU Notice of Privacy Practices has been updated recently to reflect OHSU’s commitment to providing inclusive patient care and to comply with applicable state and federal civil rights laws (Section 1557). It’s important that your subjects receive this information. If you work with research participants, you should recycle outdated, printed versions of the notice and replace them with the new 2017 versions. Also, if you post it to your website, be sure to update it there as well.

The Notice of Privacy Practices is a provision of HIPAA. All patients have the right to receive this notice–and, importantly for researchers, research subjects who have not been previously treated at OHSU may need to receive the notice if the research provides standard care along with the experimental procedures.

The new notice, with an effective date Jan. 1, 2017, is available here in English (also large font), Chinese, Spanish, Russian and Vietnamese. If you have any questions, please contact Information Privacy and Security at oips@ohsu.edu or 503-494-0219. You can also read more on O2.

OSLER TL1 Predoctoral and Postdoctoral Mentored Career Development Opportunity

The Oregon and Clinical Translational Research Institute (OCTRI) is accepting letters of intent from predoctoral and postdoctoral trainees for a TL1 mentored career development award funded by NIH National Center for Advancing Translational Sciences (NCATS).  Graduate or professional students and postdoctoral trainees at OHSU, Portland State University, University of Oregon and Oregon State University are eligible to apply.

The TL1, which is similar to an NRSA T32, supports training and career development in clinical and translational research for one year with an opportunity to extend to 3 years for training for PhD graduate students and postdoctoral fellows.  All research proposed for this program must involve either clinical or translational research defined as involving human subjects or populations, or research with application to human health.

Letter of Intent Deadline:  April 28, 2017

Learn more about the OSLER TL1 opportunity

Who’s presenting at Research Week 2017? Announcing this year’s keynotes

Another Research Week is on the horizon, and with it comes another round of engaging keynote speakers!

Nicholas J. Strausfeld, Ph.D.

N. J. Strausfeld 3The student’s choice keynote presenter this year is Nicholas J. Strausfeld, Ph.D., Regent’s Professor in the Department of Neuroscience at the University of Arizona. His talk “Half a billion year old brains and those of today: What is different?” will highlight the functional organization of the arthropod visual system and the evolution of brains; the latter focusing on the identification of evolutionarily conserved ground patterns of neuronal organization of centers mediating visual perception, allocentric memory, and action selection. Strausfeld received his Ph.D. from the University College London. He went on to complete his first year of postdoctoral research at the University of Frankfurt as an Alexander von Humboldt Fellow. He also spent time at the Max Planck Institute for Biological Cybernetics in Tubingen and at the European Molecular Biology Laboratory before joining the Division of Neurobiology at the University of Arizona. He is a recipient of several awards and honors including the John Simon Guggenheim Memorial Foundation Fellowship and the John D. and Catherine T. MacArthur Foundation Fellowship. He is the author of two books and currently serves as director of the University of Arizona’s Center for Insect Science.
Tuesday, May 2, 12 to 1 p.m., OHSU Auditorium

Reshma Jagsi, M.D., D.Phil.

jagsi-oncology226Reshma Jagsi, M.D., D. Phil., professor and deputy chair in the Department of Radiation Oncology, and research investigator in the Center for Bioethics and Social Sciences Medicine at the University of Michigan will be presenting the second keynote lecture. Her talk, “The Promise of Translational Research for Improving the Quality of Care:  The Example of Breast Radiotherapy,” is intended to inspire a general Research Week audience with examples of diverse types of research and how they all tie together, ranging from basic translational biology and translational physics to clinical trials to observational comparative effectiveness and trials of decision aids to promote translation of evidence from trials into practice. In addition to her medical training at Harvard Medical School, she served as a fellow in the Center for Ethics at Harvard University and completed her doctorate in Social Policy at Oxford University as a Marshall Scholar. She is active in organized medicine and currently serves as the Chair of the Research Committee of the Radiation Oncology Institute, as the Chair of ASCO’s Ethics Committee, and as a member of the Steering Committee of the AAMC Group on Women in Medicine and Science. She is the author of over 100 publications in peer-reviewed journals, serves as Senior Editor of the International Journal of Radiation Oncology, Biology, Physics, and is on the editorial boards of the Journal of Clinical Oncology and JAMA Oncology.

Wednesday, May 3, 3 to 4 p.m., OHSU Auditorium

Stay tuned for more events as the agenda for Research Week 2017 is finalized.

Jacob Raber’s team sheds new light on diet and genetics in cognitive impairments

High-fat diet-induced metabolic and cognitive impairments in spatial memory are more pronounced in E4 than E3 mice.

High-fat diet-induced metabolic and cognitive impairments in spatial memory are more pronounced in E4 than E3 mice.

New OHSU research suggests that the risk of developing Alzheimer’s disease is elevated in people with insulin resistance, the effects of which may be ameliorated by a low-fat diet. The study, published in the journal Scientific Reports, was led by Jacob Raber, Ph.D., professor of behavioral neuroscience, neurology, and radiation medicine, School of Medicine, and sheds new light on the shared mechanisms that could explain the overlapping pathophysiology of genetic risk factor and diet.

A diet high in saturated fats is a primary contributor to obesity, insulin resistance, and Type 2 diabetes. Both Type 2 diabetes and insulin resistance increases a person’s risk of developing Alzheimer’s disease. Genetic factors, such as the APOE gene isoform e4 encoding apoE4 (E4), also increase this risk. The new findings suggests that diet-induced insulin resistance combined with the genetic risk factor E4 act synergistically to worsen cognitive dysfunction.

Isolating the interaction between diet and E4 in humans is challenging due to dietary variations and multiple genetic factors. The team used mouse models expressing human apoE isoforms to examine the co-workings of these genetic and lifestyle factors.

A central question in the study was whether, due to differences in brain metabolism, E4 mice are more susceptible to the effects of insulin resistance than mice carrying E3, a more common isoform of the APOE gene. Both E3 and E4 mice were fed a high-fat diet for five months to induce insulin resistance. Although both groups displayed impaired memory and cognition, E4 mice exhibited significant problems in spatial learning and memory.

Raber’s team then identified significant alterations in three essential energy metabolism pathways: purine metabolism, glutamate metabolism, and the pentose phosphate pathway. The results suggest that carriers of E4 are more susceptible to metabolic impairments brought on by insulin resistance, which in turn impact memory. However, the metabolism, memory, and cognition problems caused by the high-fat diet were resolved after the E4 mice went on a low-fat diet for one month. This suggests a functional role was associated with reversal of the three metabolic pathways. The new knowledge may guide development of novel therapies for cognitive decline and dementia, but as for now, a healthy diet is in order.

In addition to Raber and lead author Lance A. Johnson, the research team included Soren Impey, Jan F. Stevens, and Eileen Ruth S. Torres.

The research was supported by the National Institute of Environmental Health Sciences (T32-ES07060 to L.A.J.); National Institutes of Health (T32-HL094294), National Science Foundation (SMA-1408653), an OHSU Tartar Trust Fellowship, the Oregon Tax Checkoff Program for Alzheimer’s Research administered by the Layton Aging & Alzheimer’s Disease Center in collaboration with the Oregon Partnership for Alzheimer’s Research, the Collins Medical Trust, and the OHSU development account of J.R.; National Institutes of Health (R21AG043857 to N.A.); NIH (S10RR027878 to J.F.S.); and the OHSU Mass Spectrometry Core Facility of the Environmental Health Sciences Center grant P30ES000210.

NIH introduces new resources for multi-site clinical trials and research studies

The NIH National Center for Advancing Translational Sciences has launched a Trial Innovation Network that provides infrastructure and resources to multi-site clinical trials and research studies.

Currently, NIH Clinical and Translational Science Award program sites, including the Oregon Clinical & Translational Research Institute, are serving as local hubs in the network. OCTRI’s research team will support OHSU investigators in designing multi-center research, as well as providing information on national resources available through the network. They will be hosting an information session as well:

Trial Innovation Network: An information session
Monday, April 10
12 to 1 p.m.
Mackenzie Hall, room 1115

The goal of the Trial Innovation Network is to address barriers to launching multi-site clinical trials and research projects, including trial-expediency and cost-efficiency. The network will also serve as a national laboratory for understanding and innovating the process of conducting clinical trials.

Contact Kitt Swartz, OCTRI Trial Innovation Network project manager, to set up a time to discuss your research or to have general questions answered.

Welcome to the Research News Blog

Welcome to the Research News Blog

OHSU Research News is your portal to information about all things research at OHSU. Find updates on events, discoveries, and important funding information.

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