NIH News

Further guidance on new NIH application requirements, Mar. 9

Over the past few months, we’ve been reporting on changes to NIH grant application guidelines, many of which are meant to enhance rigor, transparency, and reproducibility of NIH-funded research. For those of you who are still uncertain about how to address rigor in your NIH applications, Research Funding and Development Services will be holding a workshop to review the new guidelines and answer any questions you may have: Wednesday, Mar. 9 1:30 to 2:30 p.m. Mackenzie … Read More

Clarification from NIH on recent grant policy changes

On Jan. 28, NIH Deputy Director for Extramural Affairs Mike Lauer published the first in a series of blog posts addressing recent NIH policy changes related to rigor and transparency. The Open Mike series will focus on four key areas related to reproducible research: scientific premise, rigorous experimental design, consideration of relevant biological variables, and authentication of key biological and chemical resources. The first post examines scientific premise and why it warrants special consideration in grant review. … Read More

Timing of proposal submissions may influence success rates

Does the thought of writing your grant proposal leave you standing in a puddle of procrastination? Is a looming deadline the only thing that can force you to put pen to paper? New data from NIH on success rates of proposals submitted long before the deadline vs. those that come in just under the wire may motivate you to resist task avoidance and get those grants in early. In a Dec. 30, Open Mike blog … Read More

Clarifications on new NIH requirement to consider sex as a biological variable

This past summer, we reported on a new NIH policy that goes into effect Jan. 25, 2016, requiring a deliberate approach to the consideration of sex as a biological variable (SAVB) in pre-clinical research. In a Dec. 11 Open Mike blog post, Deputy Director for Extramural Research Michael Lauer, Ph.D., clarified the application and review process and provided additional information on the origins of the policy. A current high-priority focus at NIH is improved rigor and transparency in federally … Read More

NIH up for budget increase, releases strategic plan

NIH to receive $2 billion budget increase A massive federal spending bill released on Dec. 16 provides the National Institutes of Health with a $2 billion funding increase, the agency’s first raise in more than 12 years. The bill was passed on Dec. 18. The bill provides the following for medical and healthcare-related research: $200 million to the Obama administration’s Precision Medicine Initiative $350 million increase for Alzheimer’s disease research $85 million increase for the BRAIN Initiative … Read More

The call to modernize graduate education

In a Nov. 30, Feedback Loop Blog post, National Institute of General Medical Sciences (NIGMS) leadership detailed the need to modernize how graduate students in biomedical research are educated and trained. Drs. Shiva Singh, Alison Gammie, and Director Dr. Jon Lorsch announced efforts NIGMS is undertaking to catalyze an education system that has remained virtually unchanged in 30 years, even as science has evolved at an unprecedented rate. The authors make the case that the growth … Read More

NIH health economics research funding priorities defined

Health economics is used to promote health through the study of health care and health-related services, their costs and benefits, and how they are distributed among individuals and groups in society. This broad field has multiple lines of inquiry with various federal agencies providing research funding based on institutional priorities. In addition, demand for healthcare economics research continues to grow alongside rising costs and disparities. Perhaps in response to these factors, the NIH recently issued a … Read More

NIH requests for information: Optimizing NHLBI trials and improving diversity in the physician scientist workforce

1) The National Heart, Lung, and Blood Institute (NHLBI) is seeking input from the clinical trials community on how to optimize the trials NHLBI supports and administers. Of particular interest are performance milestones and metrics for selection, design, planning, conduct, and management of clinical trials including timely reporting of results to enhance scientific and public health impact. Critical elements identified by the community can then be addressed in Funding Opportunity Announcements to help guide investigators … Read More

Revised instructions on K99/R00 eligibility

On November 17, the NIH issued a clarification of the eligibility guidance for investigators applying to the “NIH Pathway to Independence Award (Parent k99/R00)” as follows: Part 2. Section III.1. Eligible Applicants Current Instruction Eligible Individuals (Program Director/Principal Investigator) K99 applicants must have no more than 4 years of postdoctoral research experience at the time of the initial or the subsequent resubmission or revision application, and must be in mentored, postdoctoral training positions to be eligible … Read More

NIH update on Precision Medicine Initiative Cohort Program

NIH Director, Francis Collins, released a statement on November 17, 2015 about progress made toward establishing a national research cohort that will be involved in  implementing the President’s Precision Medicine Initiative (PMI). The cohort will consist of roughly one million volunteers from all walks of life who will share genetic data, biological samples and diet/lifestyle information to lay the scientific foundation for precision medicine. According to Collins, the following has already been accomplished since mid-September of this year: The … Read More

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