OHSU scientists: you have a new technology available to you–with special pilot pricing available. Several new methods for genome engineering have been introduced in recent years, the most successful of which is the clustered regulatory interspaced short palindromic repeats (CRISPR)/Cas9 system. The OHSU Transgenic Mouse Models Core (TMM) has initiated several preliminary CRISPR pilot projects based in part on a recent campus-wide interest survey. Recently, OHSU’s first F1 mice genetically modified using CRISPR mice were produced by the TMM (Lev Fedorov, Ph.D., Director), in collaboration with the lab of Peter Barr-Gillespie, Ph.D. At least four different knockout alleles of the Espnl gene were generated; these required less than six weeks from initiation of the project to F0 mice. All alleles transmitted to the F1 generation. In addition, the TMM has currently initiated pilot CRISPR knock-in projects to optimize methodologies for this approach and is prepared to extend pilot program pricing to other OHSU investigators for a limited time. For additional details, visit the TMM website.
Welcome to the Research News Blog
OHSU Research News is your portal to information about all things research at OHSU. Find updates on events, discoveries, and important funding information.
Recent Blog Posts
- Oral antibiotics after C-section may reduce infection risk for obese women
- Got big data? Meet Research Data Storage
- Collaborator of Mitalipov and Amato to speak on genome-wide target specificity of CRISPR base editors
- Casey Williamson on Traumatic Brain Injury Symposium: From Research to Recovery, Sept. 15–16
- cara bolles on Traumatic Brain Injury Symposium: From Research to Recovery, Sept. 15–16
- Ashurai on OHSU researchers: New discovery on obesity-high blood pressure relationship
Awards Basic research Brown bag Cancer Career development Clinical research Collaboration Community Conference Cores Discoveries eIRB Event events Funding Funding focus funding opportunities Funding Opportunity Graduate students Internal funding IRB notes Junior faculty Lecture Limited submission Neuroscience NIH OCTRI OHSU faculty OHSU Knight Cancer Institute OHSU researchers ONPRC Postdoctoral fellows Research Research administration Research career development Research integrity Research resources Research week Seminar Technology training Translational research TTBD Visiting speaker workshop