Transgenic Core up and running in the Biomedical Research Building

OHSU’s Transgenic Mouse Models Core is up and running after relocating to a new laboratory space in the Biomedical Research Building. The new space takes advantage of the mouse pathogen-free barrier inside of the Department of Comparative Medicine.

Services provided by the Transgenic Core for both OHSU and external customers include:

  • Generation of transgenic mice, knockout mice, cryopreservation of mouse embryos and the rederivation of contaminated mouse lines.
  • In vitro fertilization and Speed Cryopresevation.
  • Services for standard molecular genetics such as genomic and plasmid DNA purification, PCR primer design, PCR genotyping and other services.
  • Personnel training for the generation of genetically modified animals and other methods.
  • Project advice and letters of support to investigators for grant applications.
  • Coming soon! Zinc-finger nuclease technology, an alternative gene targeting technique.
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