Peter Steyger, PhD, publishes ‘intensely personal’ breakthrough on drug-induced deafness

This figure from Dr. Steyger's paper illustrates how antibiotics are "trafficked" to inner ear hair cells.

As a child, Peter Steyger, Ph.D., was given an aminoglycoside antibiotic to treat a severe case of meningitis. While this type of antibiotic is incredibly effective at treating life-threating infections, Dr. Steyger can tell you all about one of the drug’s potential side effects: deafness.

Forty-eight years later, Dr. Steyger has finally discovered how those antibiotics caused his hearing loss. He found that the antibiotics cross a “blood-layrinth” barrier in the inner ear that transports essential nutrients. By finding this barrier, he hopes that researchers can eventually block the antibiotics from crossing it, thereby preventing deafness in as many as 50,000 Americans per year.

Dr. Steyger’s paper, published earlier this month in Nature’s Scientific Reports, is definitely worth the read. He’s been at the Oregon Hearing Research Center at OHSU for the past 14 years, where he is an associate professor of otolaryngology/head and neck surgery.

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Comments

  1. Antibiotics are extremely harmful! Doctor Steyger has made an incredible discovery. Despite the difficulties he had as a child, he has found a way to cope. I congratulate him!

  2. Congrats, Dr Steyger! I know this is a great breakthrough – for you and for all the other people impacted (past and future).

  3. Thank you both, Yanislav and Shannon, for your kind words.

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