Sick and tired? OHSU researchers may have found a solution

Image: Craig Dennis/Flickr
A team of OHSU researchers, led by Daniel Marks, M.D., has discovered the brain mechanism that makes us feel tired when we’re sick. Sickness-induced fatigue, they found, happens in the orexin system, which regulates sleep and arousal. The good news? Treatments of sleep disorders using orexin have been studied for years. According to Dr. Marks, this should speed the time it takes to translate their research findings into a clinical treatment for tired, unmotivated patients with chronic disease.
View the full paper, published in the Journal of Neuroscience, or read the OHSU News release.

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