OHSU researchers find possible link between neurodegenerative diseases and cancer
New research by OHSU’s Glen Kisby, PhD, Peter Spencer, PhD, and collaborators, suggests that there may be a connection between neurodegenerative diseases, like amyotrophic lateral sclerosis (ALS) and Alzheimer’s, and cancer. Drs. Kisby and Spencer came to this conclusion by studying the effects of methylazoxymethanol (MAM), a genotoxin that appears to act as both a neurotoxin and a carcinogen, in both humans and animal models.
According to Dr. Kisby: “The overlap of molecular pathways implicated in cancer and neurodegeneration may indicate the possibility of developing novel therapeutic approaches for both groups of disorders.”
To learn more, check out the paper in PLoS ONE or view the OHSU News release.
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