Join the Department of Integrative Biosciences at noon on Wednesday, March 2 for a seminar lead by Kirsten J. Lampi, MS, PhD, Professor of Integrated Biosciences at OHSU. Dr. Lampi will be speaking about: “The “Subtleties” of Structural Changes that lead to Protein Aggregation in the Lens.” The seminar will be held in the School of Dentistry, Room 606.
All the major protein aggregation diseases, such as Alzheimer’s, share common features with cataracts – protein damage followed by unfolding, aggregation, and eventually precipitation of the proteins. However, proteases and chaperones are present in the lens to prevent the accumulation of damaged proteins and to keep them in solution. This talk will focus on the current knowledge of the balance between unfolding and chaperone activity in the lens in order to maintain lens transparency. It is estimated that the cost of cataract surgery to the US Medicare system is about 3 billion a year. Being able to prevent or delay the onset of cataract surgery potentially has significant cost savings.
Questions? Contact Jackie Powell.