| Sunday July 30th |
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| 4:00pm – 7:00pm: |
Registration and hotel check-in |
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| 7:00pm – 9:00pm: |
Cocktail reception |
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| Monday July 31st |
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7:30am |
Continental breakfast |
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| 8:30am-8:45am |
Jorge H. Crosa, Oregon Health and Science
University, USA:
Welcome and Opening remarks |
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| 8:45am – 12:45pm: |
Session I: Biochemical, Genetic & Structural
Basis of Metal Uptake
I
Chair: Hans Vogel
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| 8:45am-9:20am |
Dick van der Helm, University
of Oklahoma, USA: The Beauty of Biometals |
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| 9:20am-9:55am |
Jose M. Arguello, Worcester Polytechnic Institute, US: Structure-function
of metal-binding and ATP-binding domains in P1B-type heavy
metal transport ATPases |
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| 9:55am-10:30am |
Susan Buchanan, National Institute of Health, USA: Transport
of siderophores and colicins across bacterial outer membranes |
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| 10:30am-11:00am |
Coffee Break |
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| 11:00am-11:35am |
Ranjan N. Chakraborty, East Tennessee State University, USA:
Molecular mechanism of ferric-siderophore passage through the
outer membrane receptor preoteins of E.coli |
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| 11:35am-12:10pm |
Nick LeBrun, University of East Anglia, UK: Copper-binding
properties of the soluble domains of B. subtilis CopA |
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| 12:10pm-12:45pm |
Wolfram Meyer-Klaucke, EMBL Hamburg, Germany: Metal binding
sites in Fur characterized by X-Ray absorption spectroscopy |
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| 1:00pm – 3pm: |
Complimentary lunch and free time |
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| 1:30pm – 2:30pm: |
Additional time for posters to go up |
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| 3pm – 7pm: |
Session II: Metal Homeostasis I
Chair: Guenther
Winkelmann
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| 3:00pm-3:35pm |
Greg Anderson, Queensland Institute of Medical Research,
Australia: Regulation of systemic iron homeostasis: How the
body responds to changes in iron demand |
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| 3:35pm-4:10pm |
Larry Barton, University of New Mexico, USA: Metal stress
response in bacteria and stabilization of the metalome |
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| 4:10pm-4:45pm |
Caroline Enns, Oregon Health & Science University, USA:
Hereditary hemochromatosis: A dysfunctional family of proteins |
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| 4:45pm-5:15pm |
Coffee Break |
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| 5:15pm-5:50pm |
Paul Fox, Cleveland Clinic, USA: Ceruloplasmin and iron metabolism:
still more surprises |
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| 5:50pm-6:25pm |
Tomas Ganz, UCLA, USA: The role of hepcidin in iron homeostasis |
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| 6:25pm-7:00pm |
Zena Leah Harris, Johns Hopkins Hospital & School of
Medicine, USA: Iron homeostasis and the multicopper oxidases |
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| 7pm – 8:30pm: |
Dinner |
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| 8:30pm – 10:00pm: |
Poster Session I |
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| Tuesday Aug 1st |
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| 7:30am |
Continental breakfast |
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| 8:30am – 1:15pm: |
Session III: Cell Response to Metal Misbalance; Metal & Disease
I
Chair: Klaus Hantke |
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| 8:30am-9:05am |
Jim Camakaris, University of Melbourne, Australia: Role and
regulation of the Menkes copper-translocating ATPase in health
and disease |
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| 9:05am-9:40am |
Sandra Armstrong, University of Minnesota, USA: Bordetella
iron transport and virulence |
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| 9:40am-10:15am |
Nick Cianciotto, Northwestern University Medical School,
USA: Iron acquisition by Legionella pneumophila |
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| 10:15am-10:45am |
Coffee Break |
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| 10:45am-11:20am |
Eric Skaar, Vanderbuilt University, USA,: Intracellular metalloporphyrin metabolism in Staphylococcus aureus and Bacillus anthracis |
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| 11:20am-12:05pm |
Dominique Expert, Institut National Agronomique, France:
Metabolism of iron during infection of Arabidopsis thaliana by
the phytopathogen Erwinia chrysanthemi |
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12:05pm-12:40pm |
Anne Marie Roussel, University Joseph Fourier,
France: Is selenium a predictive factor of longevity? |
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| 12:40pm-1:15pm |
Susan Hayflick,
Oregon Health & Science University, USA:
Genetic factors in neurodegeneration with brain iron accumulation |
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| 1:15pm – 3pm: |
Complimentary lunch and free time |
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| 3pm – 6:25pm: |
Session IV: Metal Transport I
Chair: Berthold Matzanke-Markstein |
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| 3:00pm-3:35pm |
Jack Kaplan, University of Illinois at Chicago, USA: Copper
entry into human cells: The role of hCTR1 |
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| 3:35pm-4:10pm |
Luis Actis, Miami University, USA: Iron acquisition in the
dental pathogen Actinobacillus actinomycetemcomitans.
What does it use as a source and how does it get this essential
metal? |
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| 4:10pm-4:45pm |
Phillip E. Klebba, University of Oklahoma,
USA: Mechanism of ferric enterobactin transport through FepA |
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| 4:45pm-5:15pm |
Coffee Break |
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| 5:15pm-5:50pm |
Mark S. Thomas, University of Sheffield,
UK: Genetic analysis of iron uptake pathways in Burkholderia
cenocepacia |
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| 5:50pm-6:25pm |
Guenther Winkelmann, University of Tuebingen, Germany: Ecology
of siderophores |
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| 7:00pm – 8:30pm: |
Dinner |
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| 8:30pm: |
Free Evening |
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| Wednesday Aug 2nd |
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|
| 7:30am |
Continental breakfast |
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| 9:00am – 1pm: |
Session V: Regulation I
Chair: Jorge H Crosa |
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| 9:00am-9:35am |
Igor Stojiljkovic Memorial Lecture: Volkmar
Braun, University of Tuebingen, Germany: Fec-type transcription
regulation in bacteria |
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| 9:35am-10:10am |
Rick Eisenstein, University of Wisconsin, USA: The Fe-S cluster
is not required for iron regulation of iron regulatory protein
1 |
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| 10:10am-10:45am |
Arnoud van Vliet, Erasmus Medical Center Rotterdam, Netherlands:
Metal-responsive gene regulation in Helicobacter pylori via
regulatory cross-talk: Hierarchical structure or organized
chaos? |
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| 10:45am-11:15am |
Coffee Break |
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| 11:15am-11:50am |
John Helmann, Cornell University, USA: Functional specialization
within the Fur family of metalloregulators |
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| 11:50am-12:25pm |
Andy Johnston, University of East Anglia, UK: Living without
Fur: The subtlety and complexity of iron-responsive gene regulation
in the symbiotic bacterium Rhizobium |
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| 12:25pm-1:00pm |
Elizabeth Theil, CHORI & UC Berkely, USA: Coordinating
oxygen and iron stress responses with DNA and mRNA promoters:
The ferritin story |
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| 1:00pm – 2:30pm: |
Complimentary lunch and free time |
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| 3pm – 7pm: |
Session VI: Metal Homeostasis II
Chair: Svetlana
Lutsenko |
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| 3:00pm-3:35pm |
Ann Hubbard, JHU School of Medicine, USA: Cu-ATPases in polarized
epithelia |
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| 3:35pm-4:10pm |
Simon Labbe, University of Sherbrooke, Canada: Molecular
control of iron homeostasis in fission yeast |
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| 4:10pm-4:45pm |
Berthold F. Matzanke-Markstein, Medizinische Universitaet
Luebeck, Germany: Iron minerals in archaea and bacteria: old
functions and novel insights |
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| 4:45pm-5:15pm |
Coffee Break |
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| 5:15pm-5:50pm |
Tracey Rouault, National Institue of Health, USA: The role
of iron regulatory proteins in mammalian iron homeostasis |
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| 5:50pm-6:25pm |
Gary Sawers, John Innes Centre, UK: Maturation of metalloproteins |
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| 6:56pm-7:00pm |
Hajo Haase, RWTH Aachen University, Germany: Signal transduction
in monocytes: the role of zinc ions |
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| 7:00pm – 8:30pm: |
Dinner |
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| 8:30pm – 10:00pm: |
Poster Session II |
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| Thursday Aug 3rd |
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| 7:30am |
Continental Breakfast |
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| 9:00am – 12:25pm: |
Session VII: Metal Transport II
Chair: Wolfgang
Koester |
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| 9:00am-9:35am |
Andrew T. McKie, Kings College London, UK: Recent advances
in transmembrane heme transport |
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| 9:35am-10:10am |
Michael Vasil, University of Colorado Health Sciences Center,
USA: How we learnt about iron acquisition in Pseudomonas
aeruginosa: a series of very fortunate events |
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| 10:10am-10:45am |
Francis Biville, Institut Pasteur, France: Hemophore-mediated
heme acquisition and signalling in Serratia marcescens |
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| 10:45am-11:15am |
Coffee Break |
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| 11:15am-11:50am |
Klaus Hantke, University of Tuebingen, Germany: Salmochelin,
a disguised Enterobactin |
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| 11:50am-12:25pm |
Manuel Lemos, University of Santiago de Compostella, Spain:
Hemin, an iron supply for vibrio species |
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| 1:00pm – 2:30pm: |
Complimentary lunch and free time |
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| 3pm – 7pm: |
Session VIII: Cell Response to Metal Misbalance;
Metal & Disease II
Chair: Caroline Enns |
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| 3:00pm-3:35pm |
Svetlana Lutsenko, Oregon Health & Science University,
USA: Molecular events associated with copper accumulation in
the liver of Wilson disease gene knock-out mice |
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| 3:35pm-4:10pm |
Mattias Hentze, EMBL Heidelberg, Germany: The IRE/IRP Regulatory System in Cellular, Organ, and Systemic Iron Homeostasis. |
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| 4:10pm-4:45pm |
Robert C. Hider, Kings College London, UK: The application
of chelators in the treatment of neurodegeneration |
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| 4:45pm-5:15pm |
Coffee Break |
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| 5:15pm-5:50pm |
Robert Maier, University of Georgia, USA: Nickel binding
accessory proteins involved in the maturation of nickel enzymes
in Helicobacter pylori |
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| 5:50pm-6:25pm |
Robert Perry, University of Kentucky, USA: Roles of the Yfe
and Feo transporters of Yersinia pestis in iron uptake
and intracellular growth |
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| 6:25pm-7:00pm |
Elizabeth Wyckoff, University of Texas at Austin, USA: Iron
uptake and regulation in the human pathogen Vibrio cholerae |
|
| 7pm – 8:30pm: |
Dinner |
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| 8:30pm: |
Free Evening |
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| Friday Aug 4th |
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| 7:30am |
Continental breakfast |
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| 9:00am – 1pm: |
Session IX: Biochemical, Genetic & Structural
Basis of Metal Uptake II
Chair: Dick van der Helm |
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| 9:00am-9:35am |
Hans Vogel, University of Calgary, Canada: TonB, or not TonB:
That is the question |
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| 9:35am-10:10am |
Kathleen Postle, Pennsylvania State University, USA: TonB-dependent
energy transduction between membranes |
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| 10:10am-10:45am |
Vinzenz Unger, Yale University, USA: What does the structure
of hCTR1 tell us about the mechanism of copper uptake |
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| 10:45am-11:15am |
Coffee Break |
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| 11:15am-11:50am |
William E. Walden, University of Illinois at Chicago, USA:
Crystal structure of the IRP1:IRE complex: Insights into the
FeS cluster switch |
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| 11:50am-12:25pm |
Dennis Winge, University of Utah, USA: Assembly of mitochondrial
cytochrome c oxidase: Involvement of a novel matrix copper
pool |
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| 12:25pm-1:00pm |
Iain Lamont, University of Otago, New Zealand: Siderophore Uptake and Signalling in Pseudomonas aeruginosa |
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| 1:00pm – 2:30pm: |
Complimentary lunch and free time |
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| 3pm – 7pm: |
Session X: Igor Stojiljkovic Memorial
Fellowship Award Presentations
Chair: Jorge H Crosa |
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| 3pm – 3:35pm: |
Post-Doc 1 |
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| 3:35pm – 4:10pm: |
Post-Doc 2 |
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| 4:15pm – 4:50pm: |
Grad Student 1 |
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| 4:50pm – 5:25pm: |
Grad Student 2 |
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| 5:30pm – 7:30pm: |
Free Time |
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| 7:30pm – 9:00pm: |
Banquet |
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| 9:00pm - on |
Music with Pat O'Neal Jazz Band and Drinks |
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| Saturday Aug 5th |
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| 7:30am |
Continental breakfast |
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| 12:00pm – 1:30pm: |
Complimentary lunch |
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| 2:00pm |
Buses Leave for Excursions |
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| Rest of day: Free Time |
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| Sunday Aug 6th |
Departure |
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