logo spacer Svetlana Lutsenko , Associate Professor
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Email: lutsenko@ohsu.edu
Office phone: 503-494-6953
Fax: 503-494-8393
B.S. (Hon.), Biochemistry">
  • Barnes,N.,Tsivkovskii,R.,Tsivkovskaia,N.,Lutsenko,S. (2005) The copper-transporting ATPases, Menkes and Wilson disease proteins, have distinct roles in adult and developing cerebellum">
  • Efremov,R.,Kosinsky,Y.A.,Nolde,D.E.,Tsivkovskii,R.,Arseniev,A.S.,Lutsenko,S. (2004) Molecular modeling of the nucleotide-binding domain of the Wilson' disease protein: location of the ATP-binding site, domain dynamics, and potential effects of the major disease mutations.">
  • Morgan,C.T.,Tsivkovskii,R.,Kosinsky,Y.A.,Efremov,R.,Lutsenko,S. (2004) The distinct functional properties of the nucleotide-binding domain of ATP7B, the human Copper-transporting ATPase. Analysis of the wilson disease mutations E1064A, H1069Q, R1151H, and C1104F.">
  • Ralle,M.,Lutsenko,S.,Blackburn,N.J. (2004) Copper transfer to the N-terminal domain of the Wilson disease protein (ATP7B): X-ray absorption spectroscopy of reconstituted and chaperone-loaded metal binding domains and their interaction with exogenous ligands">
  • Walker,J.M.,Huster,D.,Ralle,M.,Morgan,C.T.,Blackburn,N.J.,Lutsenko,S. (2004) The N-terminal metal-binding site 2 of the Wilsons disease protein plays a key role in the transfer of copper from Atox1">
  • Huster,D.,Lutsenko,S. (2003) The distinct roles of the N-terminal copper-binding sites in regulation of catalytic activity of the Wilson's disease protein">
  • Lutsenko,S.,Tsivkovskii,R.,Walker,J.M. (2003) Functional properties of the human copper-transporting ATPase ATP7B (the Wilson's disease protein) and regulation by metallochaperone Atox1.">
  • Tsivkovskii,R.,Purnat,T.,Lutsenko,S. (2003) Copper-transporting ATPases: The key regulators of intracellular copper concentrations.">
  • Ralle,M.,Lutsenko,S.,Blackburn,N.J. (2003) X-ray absorption spectroscopy of the copper chaperone HAH1 reveals a linear two-coordinate Cu(I) center capable of adduct formation with exogenous thiols and phosphines.">
  • Tsivkovskii,R.,Efremov,R.,Lutsenko,S. (2003) The Role of the Invariant His1069 in Folding and Function of Wilson’s disease Protein, the Human Copper-transporting ATPase ATP7B.">
  • Gerbasi,V.,Lutsenko,S.,Lewis,E.J. (2003) A Mutation in the ATP7B Copper Transported Causes Reduced Dopamine ß-Hydroxylase and Norepinephrine in Mouse Adrenal.">