ATP7B Metal Binding Sites

Below is a kinemage of metal-binding site 2. Click and drag on the image to rotate it or select a point in the model to identify the residue. [JavaMage Applet was obtained at the Kinemage Home Page.]
Below you can also view images of the MBS structure that were made based on the PDB file [MBS2 PDB]. The first one depicts the structure in ribbon format in different orientations (top, bottom, four side views). It marks the location of the two cysteines in the metal-binding site that coordinate copper and the location of the residue that sticks into the cavity below the cysteines. In MBS2, it is filled by a phenylalanine.
The corresponding figure showing electrostatic surface potential uses the same views as the figure with ribbons.
Larger, clearer images can be downloaded by clicking the corresponding links next to the figures.


		*Metal Binding Site 2*

Back to Lutsenko Lab Home Page Back to WNDP Info start Page Metal-binding sites MBS 1 [PDB] MBS 2 [PDB] MBS 3 [PDB] MBS 4 [PDB] MBS 5 [PDB] MBS 6 [PDB] Transmembrane Segments TM Segment 1 TM Segment 2 TM Segment 3 TM Segment 4 TM Segment 5 TM Segment 6 TM Segment 7 TM Segment 8 ATP-Binding Domain ATP BD structure model Alignments Cu-transporters Phylogenetic tree [RESTRICTED] WNDP mutations Links to WNDP research Lab Intranet		Below is a kinemage of metal-binding site 2. Click and drag on the image to rotate it or select a point in the model to identify the residue. [JavaMage Applet was obtained at the Kinemage Home Page.] Below you can also view images of the MBS structure that were made based on the PDB file [MBS2 PDB]. The first one depicts the structure in ribbon format in different orientations (top, bottom, four side views). It marks the location of the two cysteines in the metal-binding site that coordinate copper and the location of the residue that sticks into the cavity below the cysteines. In MBS2, it is filled by a phenylalanine. The corresponding figure showing electrostatic surface potential uses the same views as the figure with ribbons. Larger, clearer images can be downloaded by clicking the corresponding links next to the figures. Show larger figure Show larger figure



	\| Home \| Interests \| People \| Publications \| Links \| ATP7B Information \| Tools\| Designed and maintained by Tina D. Purnat (purnatt@ohsu.edu). Last update: July 25, 2004. The Lutsenko Laboratory, Department of Biochemistry and Molecular Biology, MRB 624, Mail Code L224, Oregon Health & Science University, 3181 SW Sam Jackson Pk Rd, Portland, OR 97239-3098 503-494-7501 (tel), 503-494-8393 (fax) This material is based upon work supported by the National Science Foundation under grant number MCB-0110057. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.