ATP7B Metal Binding Sites
 
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Metal-binding sites
  • MBS 1 [PDB]
  • MBS 2 [PDB]
  • MBS 3 [PDB]
  • MBS 4 [PDB]
  • MBS 5 [PDB]
  • MBS 6 [PDB]
  • Transmembrane Segments
  • TM Segment 1
  • TM Segment 2
  • TM Segment 3
  • TM Segment 4
  • TM Segment 5
  • TM Segment 6
  • TM Segment 7
  • TM Segment 8
  • ATP-Binding Domain
  • ATP BD structure model
  • Alignments
  • Cu-transporters
  • Phylogenetic tree [RESTRICTED]
  • WNDP mutations
     

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    Below is a kinemage of metal-binding site 2 to illustrate the ATP7B MBS structure. It also shows the location of the two cysteines in the metal-binding site that coordinate copper. Click and drag on the image to rotate it or select a point in the model to identify the residue.
    More information on individual MBS (including individual PDB files) can be accessed through the menu on the left.

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    Alignment of the metal-binding sites in various copper-transporting ATPases
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    metal binign sites alignment
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    Designed and maintained by Tina D. Purnat (purnatt@ohsu.edu).
    Last update: July 25, 2004.

    The Lutsenko Laboratory, Department of Biochemistry and Molecular Biology, MRB 624, Mail Code L224,
    Oregon Health & Science University, 3181 SW Sam Jackson Pk Rd, Portland, OR 97239-3098
    503-494-7501 (tel), 503-494-8393 (fax)

    This material is based upon work supported by the National Science Foundation
    under grant number MCB-0110057. Any opinions, findings, and conclusions or recommendations
    expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.