Back to Lutsenko Lab Home Page
Back to WNDP Info start Page
Back to WNDP Info start Page
- Metal-binding sites
-
- MBS 1 [PDB]
- MBS 2 [PDB]
- MBS 3 [PDB]
- MBS 4 [PDB]
- MBS 5 [PDB]
- MBS 6 [PDB]
- Transmembrane Segments
- TM Segment 1
- TM Segment 2
- TM Segment 3
- TM Segment 4
- TM Segment 5
- TM Segment 6
- TM Segment 7
- TM Segment 8
- ATP-Binding Domain
- ATP BD structure model
- Alignments
-
- Cu-transporters
- Phylogenetic tree [RESTRICTED]
- WNDP mutations
- Links to WNDP research
You can access
more detailed information about Wilson's Disease protein by clicking
on various protein components below.
 |
 |
||||||||||||||
 |
 |
 |
 |
 |
 |
 |
 |
 |
 |
|
|||||
 |
|
||||||||||||||
 |
 |
 |
|
||||||||||||
 |
 |
 |
 |
 |
|
||||||||||
 |
|
||||||||||||||
 |
 |
 |
|
||||||||||||
 |
 |
|
|||||||||||||
 |
|
||||||||||||||
 |
|
||||||||||||||
 |
 |
|
|||||||||||||
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Show larger illustrationgi|1703455 |sp|P35670 |AT7B_HUMAN Copper-transporting ATPase 2
MPEQERQITA REGASRKILS KLSLPTRAWE PAMKKSFAFD NVGYEGGLDG LGPSSQVATS TVRILGMTCQ
SCVKSIEDRI SNLKGIISMK VSLEQDSATV KYVPSVVCLQ QVCHQIGDMG FEASIAEGKA ASWPSRSLPA
QEAVVKLRVE GMTCQSCVSS IEGKVRKLQG VVRVKVSLSN QEAVITYQPY LIQPEDLRDH VNDMGFEAAI
KSKVAPLSLG PIDIERLQST NPKRPLSSAN QNFNNSETLG HQGSHVVTLQ LRIDGMHCKS CVLNIEENIG
QLLGVQSIQV SLENKTAQVK YDPSCTSPVA LQRAIEALPP GNFKVSLPDG AEGSGTDHRS SSSHSPGSPP
RNQVQGTCST TLIAIAGMTC ASCVHSIEGM ISQLEGVQQI SVSLAEGTAT VLYNPSVISP EELRAAIEDM
GFEASVVSES CSTNPLGNHS AGNSMVQTTD GTPTSVQEVA PHTGRLPANH APDILAKSPQ STRAVAPQKC
FLQIKGMTCA SCVSNIERNL QKEAGVLSVL VALMAGKAEI KYDPEVIQPL EIAQFIQDLG FEAAVMEDYA
GSDGNIELTI TGMTCASCVH NIESKLTRTN GITYASVALA TSKALVKFDP EIIGPRDIIK IIEEIGFHAS
LAQRNPNAHH LDHKMEIKQW KKSFLCSLVF GIPVMALMIY MLIPSNEPHQ SMVLDHNIIP GLSILNLIFF
ILCTFVQLLG GWYFYVQAYK SLRHRSANMD VLIVLATSIA YVYSLVILVV AVAEKAERSP VTFFDTPPML
FVFIALGRWL EHLAKSKTSE ALAKLMSLQA TEATVVTLGE DNLIIREEQV PMELVQRGDI VKVVPGGKFP
VDGKVLEGNT MADESLITGE AMPVTKKPGS TVIARSINAH GSVLIKATHV GNDTTLAQIV KLVEEAQMSK
APIQQLADRF SGYFVPFIII MSTLTLVVWI VIGFIDFGVV QKYFPNPNKH ISQTEVIIRF AFQTSITVLC
IACPCSLGLA TPTAVMVGTG VAAQNGILIK GGKPLEMAHK IKTVMFDKTG TITHGVPRVM RVLLLGDVAT
LPLRKVLAVV GTAEASSEHP LGVAVTKYCK EELGTETLGY CTDFQAVPGC GIGCKVSNVE GILAHSERPL
SAPASHLNEA GSLPAEKDAV PQTFSVLIGN REWLRRNGLT ISSDVSDAMT DHEMKGQTAI LVAIDGVLCG
MIAIADAVKQ EAALAVHTLQ SMGVDVVLIT GDNRKTARAI ATQVGINKVF AEVLPSHKVA KVQELQNKGK
KVAMVGDGVN DSPALAQADM GVAIGTGTDV AIEAADVVLI RNDLLDVVAS IHLSKRTVRR IRINLVLALI
YNLVGIPIAA GVFMPIGIVL QPWMGSAAMA ASSVSVVLSS LQLKCYKKPD LERYEAQAHG HMKPLTASQV
SVHIGMDDRW RDSPRATPWD QVSYVSQVSL SSLTSDKPSR HSAAADDDGD KWSLLLNGRD EEQYI
Designed and maintained
by Tina D. Purnat (purnatt@ohsu.edu).
Last update: July 25, 2004.
The Lutsenko Laboratory, Department
of Biochemistry and Molecular Biology, MRB 624, Mail Code L224,
Oregon Health & Science University, 3181 SW Sam Jackson Pk Rd, Portland,
OR 97239-3098
503-494-7501 (tel), 503-494-8393 (fax)
under grant number MCB-0110057. Any opinions, findings, and conclusions or recommendations
expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.