David H. Salat, Ph.D.

Undergraduate Degree
B.A. (Psychology, 1995), Rutgers University

Training at OHSU
1995-2000

Second Year Project
(1997): Does white matter matter? (Mentor: Jeri S. Janowsky, Ph.D.)

Ph.D. Dissertation
(2000): Selective neural and cognitive alterations in the prefrontal cortex with healthy aging and Alzheimer's disease (Mentor: Jeri S. Janowsky, Ph.D.)

Current position
Instructor in Radiology, Harvard Medical School, Boston, MA

E-mail: salat@nmr.mgh.harvard.edu

Background & Interests
My dissertation research in Behavioral Neuroscience at OHSU examined degenerative changes in the prefrontal cortex with healthy aging and Alzheimer's disease (AD) using structural magnetic resonance imaging techniques in human participants. This work was performed in the laboratory of Dr. Jeri Janowsky and in collaboration with Dr. Jeffrey Kaye in the Department of Neurology. I am currently an Instructor in the Massachusetts General Hospital Department of Radiology/Martinos Center for Biomedical Imaging following up my dissertation and postdoctoral research examining neural and cognitive degeneration in the brain with aging and AD. Information about my current work can be found here. Future work will focus on how cerebrovascular risk contributes to brain tissue degeneration and the development of dementia.

Publications

Salat DH, Kaye JA, Janowsky JS.
Greater orbital prefrontal volume selectively predicts worse working memory performance in older adults.
Cereb Cortex. 2002 May;12(5):494-505.
PMID: 11950767 [PubMed - indexed for MEDLINE]
Related Articles

Rosas HD, Liu AK, Hersch S, Glessner M, Ferrante RJ, Salat DH, van der Kouwe A, Jenkins BG, Dale AM, Fischl B.
Regional and progressive thinning of the cortical ribbon in Huntington's disease.
Neurology. 2002 Mar 12;58(5):695-701.
PMID: 11889230 [PubMed - indexed for MEDLINE]
Related Articles

Fischl B, Salat DH, Busa E, Albert M, Dieterich M, Haselgrove C, van der Kouwe A, Killiany R, Kennedy D, Klaveness S, Montillo A, Makris N, Rosen B, Dale AM.
Whole brain segmentation: automated labeling of neuroanatomical structures in the human brain.
Neuron. 2002 Jan 31;33(3):341-55.
PMID: 11832223 [PubMed - indexed for MEDLINE]
Related Articles

Salat DH, Kaye JA, Janowsky JS.
Selective preservation and degeneration within the prefrontal cortex in aging and Alzheimer disease.
Arch Neurol. 2001 Sep;58(9):1403-8.
PMID: 11559311 [PubMed - indexed for MEDLINE]
Related Articles

Salat DH, Stangl PA, Kaye JA, Janowsky JS.
Sex differences in prefrontal volume with aging and Alzheimer's disease.
Neurobiol Aging. 1999 Nov-Dec;20(6):591-6.
PMID: 10674424 [PubMed - indexed for MEDLINE]
Related Articles

Salat DH, Kaye JA, Janowsky JS.
Prefrontal gray and white matter volumes in healthy aging and Alzheimer disease.
Arch Neurol. 1999 Mar;56(3):338-44.
PMID: 10190825 [PubMed - indexed for MEDLINE]
Related Articles

Salat D, Ward A, Kaye JA, Janowsky JS.
Sex differences in the corpus callosum with aging.
Neurobiol Aging. 1997 Mar-Apr;18(2):191-7.
PMID: 9258896 [PubMed - indexed for MEDLINE]
Related Articles

Dougherty KD, Salat D, Walsh TJ.
Intraseptal injection of the cholinergic immunotoxin 192-IgG saporin fails to disrupt latent inhibition in a conditioned taste aversion paradigm.
Brain Res. 1996 Oct 14;736(1-2):260-9.
PMID: 8930332 [PubMed - indexed for MEDLINE]
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Last updated April 5, 2007