Bonnie J. Nagel
Assistant Professor, Psychiatry and Behavioral Neuroscience
Oregon Health & Science University School of Medicine
Email: nagelb@ohsu.edu
Major Areas: Developmental Cognitive Neuroscience, Adolescent Brain Development, Neuroimaging, Pediatric Neuropsychology
Previous Positions
Assistant Project Scientist, Psychiatry, University of California San Diego
NIMH Post-Doctoral Research Fellow, Psychiatry, University of California San Diego
Education
BS (1995) Washington State University
MS (2001) University of Memphis
PhD (2003) University of Memphis
Research Interests
My primary research focus is on examining typical adolescent brain and cognitive development using structural and functional neuroimaging and neuropsychological assessment techniques. My current work is aimed at studying how the development of executive functioning (e.g., working memory) is subserved by underlying structural and functional brain change. Specifically, I am interested in how maturation of white matter and changes in white matter architecture are related to functional improvements, such as better strategy use and faster processing speed, during higher-level executive tasks. Further, I am interested in identifying hormonal influences during puberty that may impact cognitive and neurostructural development and elucidating the neurobiological substrates of gender differences in structure and function. Additionally, I am interested in applying what is learned from these studies of typical development to other populations that are impacted by executive dysfunction and associated structural and functional brain abnormalities, including pediatric cancer survivors and adolescents with substance abuse disorders.
- Tate, S.R., Patterson, K.A., Nagel, B.J. , Anderson , K.G., Brown , S.A. Addiction and Stress in Adolescents. In Stress and Addiction: Biological and Psychological Mechanisms (Chapter 12). Elsevier. In press.
- Nagel, B.J. , Medina , K.L., Yoshii, J., Schweinsburg, A.D., Moadab, I. , Tapert, S.F. (2006). Age-related changes in prefrontal white matter volume across adolescence. NeuroReport , 17 , 1427-1431.
- Nagel, B.J. , Delis, D., Palmer, S.L., Reeves, C., Gajjar, A., Mulhern, R.K. (2006). Patterns of verbal memory impairment in children treated for medulloblastoma. Neuropsychology, 20, 105-112.
- Schweinsburg, A.D., Nagel, B.J. , Tapert, S.F. (2005). FMRI reveals alteration of spatial working memory networks across adolescence. Journal of the International Neuropsychological Society, 11, 631-644 .
- Nagel, B.J. , Barlett, V.C., Schweinsburg, A.D., Tapert, S.F. (2005). Neuropsychological predictors of BOLD response during a spatial working memory task in adolescents: What can performance tell us about fMRI response patterns? Journal of Clinical and Experimental Neuropsychology, 27, 823-839.
- Caldwell , L.C., Schweinsburg, A.D., Nagel, B.J. , Barlett, V.C., Brown , S.A. , Tapert, S.F. (2005). Gender and adolescent alcohol use disorders on BOLD response to spatial working memory. Alcohol and Alcoholism, 40 , 194-200 .
- Nagel, B.J. , Schweinsburg, A.D., Phan, V., Tapert, S.F. (2005). Reduced hippocampal volume among adolescents with alcohol use disorders without psychiatric comorbidity. Psychiatry Research: Neuroimaging, 139, 181-190.
- Nagel, B.J. , Palmer, S.L., Reddick, W.E., Glass, J.O., Helton, K.J., Wu, S., Xiong, X., Kun, L., Gajjar, A., Mulhern, R.K. (2004). Abnormal hippocampal development among pediatric patients with medulloblastoma treated with risk-adapted radiation therapy. The American Journal of Neuroradiology, 25, 1575-1582 .