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In 2003,
Dr. Stephanie Murphy joined the research faculty of
the Department of Anesthesiology and Perioperative
Medicine (APOM) at the Oregon Health & Science
University. She is a Diplomate of the American
College of Laboratory Animal Medicine, an Associate
Professor in our department, and the Director of the
APOM Core Animal Laboratories and Training.
Dr. Murphy’s main research interest and the focus of
a recently funded National Institute of Neurological
Disease and Stroke (NINDS) R01 grant is on exploring
the role of gender and female sex steroids in
perioperative stroke risk using a mouse model of
anesthetic preconditioning and experimental stroke.
She is also examining how male gender and
testosterone act in an age-specific manner during
experimental stroke in preconditioned brain.
Clinically, she is recognized for her expertise in
animal stroke models, rodent surgery and anesthesia
and breeding management of genetically engineered
mouse colonies. Dr. Murphy has published more than
two dozen articles, reviews and book chapters
related to her research and clinical interests.
Dr. Murphy received her V.M.D. and Ph.D. from the
University of Pennsylvania, where she investigated
mechanisms by which the dopaminergic system
contributes to hypoxic injury in neonatal piglet
brain. She then began a postdoctoral fellowship in
the Department of Comparative Medicine at The Johns
Hopkins University School of Medicine. During this
time she received a postdoctoral fellowship award
from the American Heart Association, Mid-Atlantic
Affiliate that allowed her to examine the
neuroprotective potential of progesterone in
cerebral ischemia using a rat focal stroke model.
After completing her postdoctoral fellowship, Dr.
Murphy accepted an appointment as Assistant
Professor in the Department of Anesthesiology &
Critical Care Medicine at The Johns Hopkins
University School of Medicine. She also received a
National Center for Research Resources (NCRR) K01
award that she applied to clarify the
neuroprotective importance of estrogen, alone or in
combination with progesterone, in postmenopausal
stroke using reproductively senescent female
rats. |
