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The entorhinal cortex, shown below in red, is the layer of grey matter tissue on a specific subregion of the parahippocampal gyrus of the temporal lobe.

Entorhinal cortex

Our tracing method measures the bilateral entorhinal cortex volumes using standard T2 images and atlas-based boundaries. Our results suggest that the entorhinal cortex volume has greater variability (see graph below) than the hippocampal body volume and therefore is not as powerful for detecting dementia as the hippocampus.
 
Brain Regions of Interest tracing results