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From the Layton Center's archives of over 2500 MRI brain scans, the images below are representative of cognitively intact adults. Each brain is identified by decade of life and by the relative degree of atrophy, compared to the brains of other same-age cognitively healthy volunteers.

In contrast, three examples of MRI scans typical of Alzheimer's patients at progressive stages of the disease can be found at the very bottom of this page.


Cognitively Intact Adults

(By clicking on an image, you are able to view a movie which displays
the entire brain scan from the back of the head to the front.)
 
How did we calculate this? Brain volumes, corrected for head size, were measured using the Layton Center's coronal analysis method. The volume of each brain identified as having an average amount of atrophy falls within the 45th to 55th percentiles of the statistical norms for that subgroup, based on hundreds of analyzed MRI brain scans. "Least atrophy" examples are from the highest 10th percentile, and "most atrophy" from the lowest 10th.
ATROPHY 60-69 yrs 70-79 yrs 80-89 yrs 90-99 yrs
Least
Average
Most



Alzheimer's Patients
Very Mild Mild Moderate