William D. Rooney, Ph.D., Staff Scientist

William Rooney

Printable version of CV

EDUCATION/TRAINING:

State University of New York, Stony Brook NY B.S. 1983 Biochemistry/Chemistry
State University of New York, Stony Brook NY Ph.D. 1990 Chemistry
University of California, San Francisco CA Post-Doc. 1991-1993 Neuro-Imaging

PROFESSIONAL EXPERIENCE AND HONORS:

1984-1990     Research Assistant, Department of Chemistry, SUNY Stony Brook, NY
1986-1990     Research Engineer, Corporate Research Center, Grumman Corp., Bethpage, NY
1988:              cited for "Excellence in Research", Stony Brook chapter of Sigma Xi
1990-1991     Staff Scientist, Corporate Research Center, Grumman Corp., Bethpage, NY
1991:              President's Award to Outstanding Graduate Students, USB, Stony Brook, NY
1991-1993     Postdoctoral (NSRA) Fellow, Department of Radiology, UCSF, San Francisco, CA
1993-1994     Research Spectroscopist, Department of Neurology, CPMC, San Francisco, CA
1994-1997     Assistant Professor of Radiology, Department of Radiology, UCSF, San Francisco, CA
1997-1999     Assistant Chemist, Chemistry Department, Brookhaven National Laboratory, Upton, NY
1999-2001     Associate Chemist, Chemistry Department, Brookhaven National Laboratory, Upton, NY
2001-2005     Adjunct Assistant Professor of Biomedical Engineering, SUNY Stony Brook, NY
2001-2005     Chemist, Chemistry Department, Brookhaven National Laboratory, Upton, NY

SELECTED PUBLICATIONS:

J.M. Papazian, J.P. Wagner, W.D. Rooney. Porosity development during heat treatment of aluminum-lithium alloys. Journal De Physique Colloque C348, C513-C519 (1987).

W.D. Rooney, T.M. Barbara, C.S. Springer, Jr. Two dimensional double quantum NMR spectroscopy of isolated I=3/2: 23Na examples. Journal of the American Chemical Society110, 674-681 (1988).

W.D. Rooney, J.M. Papazian, E. Balmuth, R.C. Davies and P.N. Adler. Elastic anisotropy of Al-Li alloys. Aluminum Lithium Alloys, 799-808 (1989), Materials and Component Engineering Publications Ltd. Birmingham, United Kingdom.

Y. Xu, T.M. Barbara, W.D. Rooney, C.S. Springer, Jr. 2D multiple quantum in I=3/2 II: 35Cl examples. Journal of Magnetic Resonance83, 279-298 (1989).

W.D. Rooney and C.S. Springer, Jr. A comprehensive approach to the analysis and interpretation of the resonances of spins 3/2 from living systems. NMR in Biomedicine4, 209-226 (1991).

W.D. Rooney and C.S. Springer, The Molecular Environment of Intracellular Sodium: 23Na NMR Relaxation, NMR Biomed, 4,227-245 (1991).

M. Lee, W.D. Rooney, and J. Whiteside. An XPS study of space-exposed polyimide film. in LDEF-Second Post Retrieval Symposium. A.S. Levine, editor NASA Publication3194-3, 957-962 (1993).

Y. Seo, W.D. Rooney, and M. Murakami. An analysis of intracellular 23Na relaxation using the double-quantum filtered NMR signal from the perfused rat salivary gland. Biochim Biophys Acta1177, 111-116 (1993).

T. Ebisu, W.D. Rooney, S.H. Graham, M.W. Weiner, and A.A. Maudsley. N-Acetylaspartate as an in vivo marker of neuronal viability in kainate induced status epilepticus. J. Cereb. Blood Flow Metab14, 373-382 (1994).

J. Whiteside, E. Kamykowski, W.D. Rooney, R. Schulte, and M. Stauber. Effects of 69 months in low earth orbit on Kapton antenna structures. Journal of Spacecraft and Rockets31, 860-865 (1994).

A Mancuso, H. Karibe, W.D. Rooney, G. Zarow, S.H. Graham, M.W. Weiner, and P.R. Weinstein. Early reduction in the apparent diffusion coefficient of water determined by MR imaging does not indicate the full extent of pathologic cerebral blood flow reduction during middle cerebral artery occlusion in rats. Magn. Reson. Med.34, 368-377 (1995).

W.D. Rooney, T. Ebisu, A. Mancuso, S. Graham, M.W. Weiner, and A.A. Maudsley. Metabolite 1H relaxation in hyponatremic brain. Magn. Reson. Med.35, 688-696 (1996).

T. Ebisu, W.D. Rooney, S.H. Graham, A. Mancuso, S Graham, M.W. Weiner, and A.A. Maudsley. MR spectroscopic imaging and diffusion-weighted MRI for early detection of kainate-induced status epilepticus in the rat. Magn. Reson. Med.36, 821-828 (1996).

D.J. Meyerhoff, W.D. Rooney, T. Tokumitsu, and M.W. Weiner. Evidence of multiple ethanol pools in the brain: An in-vivo proton magnetization transfer study. Alcoholism: Clinical and Experimental Research20, 1283-1288 (1996).

T. Higuchi, E.J. Fernandez, W.D. Rooney, H.L. Gaspary, P.R. Weinstein, S Graham, MW Weiner, and AA Maudsley. Effects of severe global ischemia on N-acetyaspartate and other metabolites in the rat brain. Magn. Reson. Med.37, 851-857 (1997).

W.D. Rooney, D.E. Goodkin, N. Schuff, D.J. Meyerhoff, D. Norman, and M.W. Weiner. 1H MRSI in multiple sclerosis normal appearing white matter. Multiple Sclerosis3, 231-237 (1997).

M. Masami, S.A. Camacho, W.D. Rooney, G. Modin, H-Z. Zhou, M.W. Weiner, and V.M. Figueredo. Increased inorganic phosphate and decreased perfusion pressure contribute similarly in mediating contractile depression during mild low-flow ischemia: evidence from graded hypoxia studies in rat hearts. American Journal of Physiology273, H566-H572 (1997).

W.D. Rooney, R.G. Miller, N. Schuff, D. Gelinas, A.A. Maudsley, and M.W. Weiner. Decreased N-acetylaspartate in motor cortex and corticospinal tract in amyotrophic lateral sclerosis. Neurol.50, 1800-5. (1998).

J. Tanabe, M. Vermathen, R.G. Miller, D. Gelinas, M.W. Weiner, and W.D. Rooney. Reduced MTR in the corticospinal tract and normal T2 in amyotrophic lateral sclerosis. Magn. Reson. Imag., 16, 1163-1169 (1998).

D.E. Goodkin, W.D. Rooney, R. Sloan, P. Bacchetti, L. Gee, M. Vermathen, M. Abundo, S. Majumbdar, S. Nelson, and M.W. Weiner. A serial study of new MS lesions and the white matter from which they arise. Neurology51, 1689-1697 (1998).

M.K. Sammi, C.A. Felder, J.S. Fowler, J-H. Lee, A.V. Levy, X. Li, J. Logan, I. Palyka, W.D. Rooney, N.D. Volkow, G-J., Wang,, and C.S. Springer, The Intimate Combination of Low- and High-Resolution Image Data: I. Real-Space PET and 1H2O MRI, PETAMRI, Magn. Reson. Med. 42, 345-360 (1999).

C.S. Landis, X. Li, F.W. Telang, J.A. Coderre, P.L. Micca, W.D. Rooney, L.L. Latour, G. Vetek, I. Palyka, and C.S. Springer,Determination of MRI Contrast Agent Concentration Time Course in Vivo Following Bolus Injection: Effect of Equilibrium Transcytolemmal Water Exchange, Magn. Reson. Med. 44, 563-574 (2000).

J. Suhy, W.D. Rooney, D.E. Goodkin, B. Soher, A.A. Capizzano, A.A. Maudsley, and M.W. Weiner . Comparison of primary progressive and relapsing remitting multiple sclerosis by 1H MRSI. Multiple Sclerosis6, 148-155 (2000)

W.D. Rooney, J-H Lee, X. Li, G-J Wang, D. Francheschi, C.S. Springer, Jr., and N.D. Volkow. 4 T Water Proton T1 Relaxation times in normal human brain and during acute ethanol intoxication. Alcoholism: Experimental and Clinical Research24, 830-836 (2000)

N.D. Volkow, G-J. Wang, J.S. Fowler, W.D. Rooney, C.A. Felder, J-H. Lee, D.J. Schlyer, J.W. Pan, S.J. Gatley, and C.S. Springer, Resting Brain Metabolic Activity in a 4 Tesla Magnetic Field, Magn. Reson. Med. 44, 701-705 (2000).

N. Schuff, W.D. Rooney, R. Miller, D.F. Gelinas, D.L. Amend, A.A. Maudsley, and M.W. Weiner. Reanalysis of multislice (1)H MRSI in amyotrophic lateral sclerosis. Magn. Reson. Med.45, 513-516 (2001).

M.F. Ochs, R.S. Stoyanova, T.R. Brown, W.D. Rooney, and C.S. Springer, A Bayesian Markov Chain Monte Carlo Solution of      the Bilinear Problem, Bayesian Inference and Maximum Entropy Methods in Science and Engineering, Eds., J.T. Rychert, G.J., Erickson, and C.R. Smith [Melville, NY] Proc. Am. Inst. Phys. 567, 274-284 (2001).

C.S. Springer and W.D. Rooney, Indirectly, Tissue is the Issue: In MRI, Contrast Reagents use the Body's Water Molecules to Enhance Signals, Mod. Drug. Discov. 4, (#10) 53-57 (2001).

C.S. Springer, W.D. Rooney, and X. Li, The Effects of Equilibrium Transcytolemmal Water Exchange on the Determination of Contrast Reagent Concentration In Vivo, Magn. Reson. Med. 47, 422-424 (2002).

H. Benveniste, J.S. Fowler, W.D. Rooney, D.H. Moller, W.W. Backus, D.A. Warner, P. Carter, P. King, B. Scharf, D. Schlyer, and N.D. Volkow. Maternal-Fetal In Vivo Imaging: A Combined MRI and PET Study. J Nucl. Med.44,1522-1530 (2003)

T.E. Yankeelov, W.D. Rooney, X. Li, and C.S. Springer. Variation of the relaxographic "shutter-speed" for transcytolemmal water exchange affects the CR bolus-tracking curve shape. Magn. Reson. Med.50, 1151-1169 (2003).

Ding Y-S, Fowler JS, Logan J, Wang GJ, Telang F, Garza V, Biegon A, Pareto D, Rooney W, Shea C, Alexoff D, Volkow ND, and Vocci F: 6-[18F]Fluoro-A-85380, a new PET tracer for the nicotinic acetylcholine receptor: Studies in the human brain and in vivo demonstration of specific binding in white matter. Synapse.53,184-189 (2004)

by airc@ohsu.edu