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Oregon Health&Science University

Department of Cell and Developmental Biology

 
 

 

How to find us:

OHSU
School of Medicine
Department of Cell and Developmental Biology
3181 SW Sam Jackson Park Rd
Basic Sciences L215
Portland, OR 97239

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Driving directions

 

 

 


Recent news

August 2014

Hillary's paper describing the role of Wnt modulator Kremen1 in the lateral line has been published in journal Development. This paper shows a surprising role for Kremen1 in positively modulating canonical Wnt activity in the lateral line primordium.

 

July 2014

Katie Drerup received a prestigious Pathway to Independence Award from NINDS. This award will support two years of her postdoctoral research ($90,000/year) and three years of her independent research ($250,000/year). The award is aimed at studying dynein-mediated transport in zebrafish.

This review describes types of multicellular rosettes that form during organ development and maintenance as well as molecular bases of their formation. Read more here>

June 2014

Here are some picks from the lab hike to Falls Creek Falls. Beatiful place!

Hike 2014

Hike 2014

Hike 2014

Hike 2014

February 2014

Ski trip on Mt Hood,

SARA

Ski trip

 

KATIE

Ski trip

THE REST

Ski trip

 

January 2014

Matt defended his thesis entitled "Origin of cranial sensory systems". Specifically, Matt studied how cranial sensory placodes (epithelial structures that give rise to the cranial sensory neurons) develop in zebrafish. Matt is moving on to his postdoc at Massachusetts General Hospital in Boston to study chemical genetics of behavior in David Kokel's lab. Congrats and Good Luck!

Matt Defense

 

September 2013

Molly successfully defended her thesis on the 4th of September. The title of her thesis project is "Regulation of cell shape during development of the nervous system". Over the course of her thesis research, Molly has studied how cells change their shapes during two distinct processes, formation of polarized epithelial rosettes and axon extension. Molly is staying in the lab until mid February, 2014 to finish her axon extension project. Molly is also writing a review article on polarized epithelial rosettes.

Here is the pic of the happy academic child and happy academic dad:

Molly_defense

March 2013

We are excited to report that Katie's paper entitled " JNK-Interacting Protein 3 Mediates the Retrograde Transport of Activated c-Jun N-Terminal Kinase and Lysosomes" has been published in journal PLoS genetics. This study establishes zebrafish as a model system for in vivo analysis of axonal transport and identifies Jip3 as a crucial adaptor for retrograde transport of pJNK and lysosomes (PUBMED).

 

January 2013

Matt McCarroll, a graduate student in the lab, received a one-year Ronny Lacroute fellowship from the Oregon Brain Institute. The fellowship will support Matt's research in identifying cues responsible for induction of cranial placodes in zebrafish. Congratulations Matt!

 

September 2012

Hike to Mt St. Helens

The braver part of the lab hiked the rim of Mt St Helens. Check it out:

Mt St Helens trailhead

On the way up:

Mt St Helens on the way up

At the rim:

Mt St Helens at the rim

View from the top (Spirit lake and Mt Adams):

Mt St Helens view

 

August 2012

Molly's study shows that FgfR-Ras-MAPK pathway regulates apical constriction in the newly forming rosettes of the posterior lateral line primordium. This pathway is responsible for the apical positioning of Rho-associated kinase which, in turn, is necessary to activate apical constriction. (Pubmed)

 

June 2012

Katie Drerup received $30,000 from the Collins Midecal Trust to study axonal transport in zebrafish. Congrats Katie!

 

June 2012

Matt's paper shows that graded levels of two transcription factors , Pax2a and Pax8, regulate differentiation of otic and epibranchial placodes in zebrafish. Matt's study also revealed that the canonical Wnt signaling pathway is responsible for maintaining high Pax levels in placodal precursors.(Pubmed).

March 2012

Hillary McGraw Won a prize for best oral presentation at the Northwest Developmental Biology Conference at Friday Harbor, WA. She won $1,000 to cover her trip to the national meeting of the Society for Developmental Biology in Montreal. The title of her talk was "Canonical Wnt signaling regulates multiple aspects of collective cell migration in the zebrafish posterior lateral line primordium".

 

September 2011

Manuscript by Maya Culbertson et al., has been published in journal PlOS ONE. This study revealed that two neural crest populations, chondrogenic and gliogenic crest, play distinct roles during epibranchial ganglia development.

 

August 2011

Manuscript by Hillary McGraw et al., has been published in journal Development. This study revealed one of the mechnisms by which progenitor cell identity is regulated during lateral line development and role of Lef1 in this process.

June 2011

Hillary received a two-year fellowship from Americah Heart Association. This fellowship will fund her research that focuses on specification of progenitor cells during organ development.

Katie and Molly receive $2000 awards from Tartar Trust to attend conference/course of their choice. Congratulations Katie and Molly!

March 2011

Katie received individual NRSA from NINDS to study axonal transport in zebrafish. Congrats Katie!

 

March 2011

Molly received first prize for best oral presentation at NWDB meeting. One thousand $$$ award will cover her travel to the national SDB meeting in Chicago. Have fun Molly!

Ferry_2011

Ferry ride

 

OHSU

OHSU community ar Friday Harbor meeting

 

August 2010

Katie Drerup received $500 prize as a runner up for best talk presented by a postdoc at the SDB meeting in Albuquerque , NM. She presented her reserach at the plenary postdoc symposium. She also received $400 award from Genentech.

katie

April 2010

Molly is the recipient of the 2010 graduate fellowship from the NSF. This prestigious award guarantees funding and tuition for 3 years. It will fund Molly's research in lateral line patterning in zebrafish. For more detail about NSF graduate fellowships click here.

Molly

August 2009

Matt McCarroll has joined our lab. Matt will continue Zack's project studying development of cranial placodes and ganglia. Welcome Matt!

matt

August 2009

Sorry to see you leave Zack, thanks for all your help with setting up the lab and establishing a number of novel techniques!

lunch1

 

April 2009

Molly Harding, a neuroscience student , has recently joined our lab. Molly is interested in lateral line development and plans to study mutants that have patterning defects during lateral line development.

molly

March 2009

North-West DB meeting at Friday Harbor Labs was fun, see it for yourself:

FHL_2009

December 2009

KatieCatherine (Katie) Drerup will join our lab as a post-doctoral scientist in March of 2009. Katie is currently finishing her thesis research at Northwestern University Interdepartmental Neuroscience Program in the laboratory of Dr. Jill Morris.

 

Hillary McGraw will start her post-doctoral research in our lab at the end of next spring. Currently, Hillary is a graduate student in the Program of Molecular and Cellular Biology at University of Washington in the laboratory of Dr. David Raible. She is scheduled to defend her thesis in the spring of 2009 and she will start her post-doctoral research in our lab shortly thereafter.

Hillary

December 2007

maya pictureMaya Culbertson has recently joined our lab. Maya has extensive experience in neuroscience research as well as some experience in zebrafish research. She obtained her B.A. in Molecular Biology from Princeton University and her Masters in Forensic Science from National University. Her recent job was at UCSD. Welcome to the lab!

zach pictureZachary Lewis graduated from Reed College in 2006 and did his post-graduate fellowship there as well. His thesis research involved studying primordial germ cell differentiation in Threespine Sticklebacks. He won a prestigious Class of '21 award for his thesis research. Big welcome!

November 2007

Thuy Thuy Huynh recently joined the lab as a fish facility manager. Thuy brings extensive experience in managing research zebrafish facility. In addition to the degree in Aquatic and Fisheries Sciences (2003) from the University of Washington, he also spent three years helping to maintain University of Washington zebrafish facility shared by four zebrafish labs.

 

 

 

 

 

 

 

 

 

 


 
   

 
             

Last update: August 2014

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